{"doi":"10.1364/ol.544499","title":"Swept-source visible-light optical coherence tomography","abstract":"We demonstrate the feasibility of swept-source visible-light optical coherence tomography (SS-vis-OCT). We used a fanout periodically poled lithium niobate (PPLN) crystal for second-harmonic generation (SHG) to convert a commercial near-infrared swept-source (NIR-SS) laser into a visible-light SS laser. To enhance SHG efficiency, we amplified the NIR-SS output with booster optical amplifiers (BOAs) and generated up to 580 µW of power. The SS-vis-OCT achieved a maximum axial resolution of 7.3 µm and an imaging depth of 5 mm in air, corresponding to 5.4 µm and 3.7 mm in tissue (n = 1.35). Compared with spectral-domain vis-OCT, SS-vis-OCT provides a 2.2-fold increased imaging depth and a 2.8-fold improved roll-off. Additionally, we validated SS-vis-OCT performance using a 3D-printed pyramid phantom, with its feature measurements cross-validated by scanning electron microscopy (SEM).","journal":"Optics Letters","year":2025,"id":517632,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":7,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9642,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":409027,"name":"Roman V. Kuranov","orcid":"0000-0002-9668-2960","position":1,"is_corresponding":false},{"id":409025,"name":"David A. Miller","orcid":"0000-0002-1630-1233","position":2,"is_corresponding":false},{"id":511425,"name":"Tingwei Zhang","orcid":"0000-0002-6375-012X","position":3,"is_corresponding":false},{"id":909453,"name":"Wei-Hong Yeo","orcid":"0000-0003-2181-1673","position":4,"is_corresponding":false},{"id":1384623,"name":"Raymond Atkinson","orcid":null,"position":5,"is_corresponding":false},{"id":1337834,"name":"Pengpeng Zhang","orcid":"0000-0001-6465-3324","position":6,"is_corresponding":false},{"id":456664,"name":"Cheng Sun","orcid":"0000-0002-2744-0896","position":7,"is_corresponding":false},{"id":409028,"name":"Hao F. Zhang","orcid":"0000-0001-5089-1196","position":8,"is_corresponding":false},{"id":998222,"name":"Weijia Fan","orcid":"0009-0002-8173-0760","position":0,"is_corresponding":true}],"reference_count":23,"raw_metadata":null,"created_at":"2026-07-19T02:48:59.410472Z","pmid":"39888790","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}