{"doi":"10.1364/ol.538165","title":"112° field of view high-resolution swept-source OCT angiography for rat retinas","abstract":"This study introduces an ultra-wide field (UWF) and high-resolution swept-source optical coherence tomographic angiography (OCTA) system for rat retinal imaging. Using an asymmetrical optics design, the system achieves unprecedented details of retinal structures and vascular plexuses over a large field of view (112°) in a single-shot acquisition. Views of single-nerve fiber bundles and single capillary vessels are consistently visible over a 112° field of view. The system has a long imaging range and high penetration and allows a full view of vitreous hyaloid vessels, retina, choroid, sclera, and posterior ciliary arteries, down to sub-sclera connective tissues. In a longitudinal study of oxygen-induced retinopathy (OIR) in rats, the system successfully revealed the progression and regression of OIR-related vascular pathologies, such as ischemia, neovascularization, and tortuosity. To our knowledge, this novel UWF-OCT/OCTA prototype designed for rat retinal imaging will be a vital tool for monitoring disease progression and evaluating therapeutic interventions in preclinical models.","journal":"Optics Letters","year":2024,"id":437347,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":11,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9467,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":644499,"name":"Shuibin Ni","orcid":"0000-0003-3146-5006","position":1,"is_corresponding":false},{"id":288601,"name":"Tristan T. Hormel","orcid":"0000-0002-7242-1934","position":2,"is_corresponding":false},{"id":98459,"name":"John C. Morrison","orcid":"0000-0003-3048-6470","position":3,"is_corresponding":false},{"id":1023282,"name":"Diana C. Lozano","orcid":null,"position":4,"is_corresponding":false},{"id":525574,"name":"Yifan Jian","orcid":"0000-0001-7988-7385","position":5,"is_corresponding":false},{"id":264208,"name":"J. Peter Campbell","orcid":"0000-0001-7964-9475","position":6,"is_corresponding":false},{"id":288604,"name":"Yali Jia","orcid":"0000-0002-2784-1905","position":7,"is_corresponding":false},{"id":889675,"name":"Guangru B. Liang","orcid":"0000-0002-6322-3899","position":0,"is_corresponding":true}],"reference_count":22,"raw_metadata":null,"created_at":"2026-07-19T02:00:29.872940Z","pmid":"39546690","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}