{"doi":"10.1364/ol.36.000148","title":"High-speed synthetic aperture microscopy for live cell imaging","abstract":null,"journal":"Optics Letters","year":2011,"id":683518,"datarank":0.7091081728068512,"base_score":4.727387818712341,"endowment":4.727387818712341,"self_citation_contribution":0.7091081728068512,"citation_network_contribution":0.0,"self_endowment_contribution":0.7091081728068512,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":112,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":2,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1785591,"name":"Youngwoon Choi","orcid":null,"position":1,"is_corresponding":false},{"id":164492,"name":"Christopher Fang-Yen","orcid":null,"position":2,"is_corresponding":false},{"id":405046,"name":"Yongjin Sung","orcid":"0000-0001-6371-8771","position":3,"is_corresponding":false},{"id":90020,"name":"Ramachandra R. Dasari","orcid":null,"position":4,"is_corresponding":false},{"id":90021,"name":"Michael S. Feld","orcid":"0000-0001-6755-5287","position":5,"is_corresponding":false},{"id":990168,"name":"Wonshik Choi","orcid":"0000-0002-9445-7081","position":6,"is_corresponding":false},{"id":1785590,"name":"Moonseok Kim","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"High-speed synthetic aperture microscopy for live cell imaging","abstract":"We present a high-speed synthetic aperture microscopy for quantitative phase imaging of live biological cells. We measure 361 complex amplitude images of an object with various directions of illumination covering an NA of 0.8 in less than one-thirteenth of a second and then combine the images with a phase-referencing method to create a synthesized phase image. Because of the increased depth selectivity, artifacts from diffraction that are typically present in coherent imaging are significantly suppressed, and lateral resolution of phase imaging is improved. We use the instrument to demonstrate high-quality phase imaging of live cells, both static and dynamic, and thickness measurements of a nanoscale cholesterol helical ribbon.","is_dataset_classified":null,"base_score":4.727387818712341,"endowment":4.727387818712341,"datacite_reuse_total":2,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"21263482","pmcid":null,"openalex_id":"https://openalex.org/W2079997120","authors":[],"funders":[{"funder_name":"Basic Science Research Program","grant_id":"20100011286","title":null},{"funder_name":"National Institutes of Health","grant_id":"P41-RR02594-24","title":null},{"funder_name":"NCRR NIH HHS","grant_id":"P41 RR002594","title":null}],"total_grants":3,"fwci":4.999,"citation_percentile":0.96165238,"influential_citations":0,"citation_trend":[{"year":2012,"count":8},{"year":2013,"count":6},{"year":2014,"count":10},{"year":2015,"count":7},{"year":2016,"count":4},{"year":2017,"count":17},{"year":2018,"count":9},{"year":2019,"count":12},{"year":2020,"count":7},{"year":2021,"count":3},{"year":2022,"count":5},{"year":2023,"count":6},{"year":2024,"count":3},{"year":2025,"count":9},{"year":2026,"count":2}],"oa_status":"closed","license":"https://doi.org/10.1364/OA_License_v1#VOR","oa_locations":[{"url":"https://www.osapublishing.org/viewmedia.cfm?URI=ol-36-2-148&seq=0","host_type":"publisher"},{"url":"https://doi.org/10.1364/ol.36.000148","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/21263482","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3068016","host_type":"repository"}],"fields_of_study":["Digital Holography and Microscopy","Optical Coherence Tomography Applications","Optical measurement and interference techniques","Cell Survival","Cholesterol","Light","Microglia","Microscopy","Molecular Imaging"],"mesh_terms":["Cell Survival","Cholesterol","Light","Microscopy","Microglia","Molecular Imaging"],"keywords":["Optics","Phase imaging","Microscopy","Biological imaging","Live cell imaging","Phase (matter)","Synthetic aperture radar","Diffraction","Interference microscopy","Materials science","Image quality","Phase retrieval","Nanoscopic scale","Resolution (logic)","Physics","Computer science","Nanotechnology","Fourier transform","Computer vision","Image (mathematics)","Chemistry","Artificial intelligence"],"sdg_mappings":[],"linked_datasets":[{"doi":"10.6084/m9.figshare.c.3754331","title":"High-speed synthetic aperture microscopy for live cell imaging","publisher":"Figshare","resource_type":"Collection"},{"doi":"10.6084/m9.figshare.c.3754331.v1","title":"High-speed synthetic aperture microscopy for live cell imaging","publisher":"Figshare","resource_type":"Collection"}],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-18T11:23:29.055364Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}