{"doi":"10.1364/boe.571276","title":"On-skin, micro-objective enabled camera module for speckle contrast optical spectroscopy/tomography","abstract":"In this paper, we introduce a speckle contrast optical spectroscopy/tomography (SCOS/SCOT) configuration based on an integrated imaging approach exploiting 113 micro-objectives mounted on a commercial CMOS camera that operates without fiber coupling, suitable for direct skin contact measurements and simultaneous multiple source-detector separation acquisitions. This compact system was validated ex vivo on phantoms and in vivo by monitoring the blood flow on the forearm muscle of a healthy human subject. The measurements, performed at multiple source-detector separations and camera exposure times, demonstrate excellent agreement with the theory based on the correlation-diffusion model. In vivo data demonstrate the capability of tracking pulsatile blood flow with a high signal-to-noise ratio (>4 harmonics of the cardiac pulse frequency detected) and sensitivity to small changes in muscle blood flow. This micro-objective array-based design overcomes a key challenge towards wearable SCOS/SCOT devices.","journal":"Biomedical Optics Express","year":2025,"id":554146,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9576,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":719402,"name":"Lorenzo Cortese","orcid":"0000-0001-9258-0863","position":1,"is_corresponding":false},{"id":1451033,"name":"Manish Verma","orcid":"0000-0001-6366-9420","position":2,"is_corresponding":false},{"id":1451034,"name":"Peter Dannberg","orcid":"0009-0000-1922-7828","position":3,"is_corresponding":false},{"id":498162,"name":"Ilias Tachtsidis","orcid":"0000-0002-8125-0313","position":4,"is_corresponding":false},{"id":1451035,"name":"Norbert Danz","orcid":"0000-0002-8927-9284","position":5,"is_corresponding":false},{"id":843770,"name":"Turgut Durduran","orcid":"0000-0001-5838-1027","position":6,"is_corresponding":false},{"id":1451032,"name":"Andrés Quiroga","orcid":"0000-0002-3846-0761","position":0,"is_corresponding":true}],"reference_count":39,"raw_metadata":null,"created_at":"2026-07-19T02:54:45.872391Z","pmid":"41112780","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}