{"doi":"10.1364/boe.526145","title":"Mechanically sheared axially swept light-sheet microscopy","abstract":"We present a mechanically sheared image acquisition format for upright and open-top light-sheet microscopes that automatically places data in its proper spatial context. This approach, which reduces computational post-processing and eliminates unnecessary interpolation or duplication of the data, is demonstrated on an upright variant of axially swept light-sheet microscopy (ASLM) that achieves a field of view, measuring 774 × 435 microns, that is 3.2-fold larger than previous models and a raw and isotropic resolution of ∼460 nm. Combined, we demonstrate the power of this approach by imaging sub-diffraction beads, cleared biological tissues, and expanded specimens.","journal":"Biomedical Optics Express","year":2024,"id":448996,"datarank":0.2905852205129473,"base_score":1.791759469228055,"endowment":1.791759469228055,"self_citation_contribution":0.26876392038420827,"citation_network_contribution":0.021821300128739018,"self_endowment_contribution":0.26876392038420827,"citer_contribution":0.021821300128739018,"corpus_percentile":null,"corpus_rank":null,"citation_count":5,"citer_count":4,"citers_with_citation_signal":1,"citers_with_endowment":1,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9468,"is_data_producer":true,"deposit_databanks":{"figshare":["10.6084/m9.figshare.26380969"]},"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":559622,"name":"Dushyant Mehra","orcid":"0000-0003-2942-8599","position":1,"is_corresponding":false},{"id":571447,"name":"Zach Marin","orcid":"0000-0001-5341-9911","position":2,"is_corresponding":false},{"id":282884,"name":"Xiaoding Wang","orcid":"0000-0003-2333-2270","position":3,"is_corresponding":false},{"id":1268359,"name":"Hazel M. Borges","orcid":"0009-0006-5834-5310","position":4,"is_corresponding":false},{"id":516140,"name":"Qionghua Shen","orcid":"0000-0002-2808-4408","position":5,"is_corresponding":false},{"id":1213274,"name":"Seweryn Gałecki","orcid":"0000-0002-7020-0804","position":6,"is_corresponding":false},{"id":1268360,"name":"John Haug","orcid":"0000-0001-8247-3271","position":7,"is_corresponding":false},{"id":1251480,"name":"Derek H. Abbott","orcid":null,"position":8,"is_corresponding":false},{"id":245883,"name":"Kevin M. Dean","orcid":"0000-0003-0839-2320","position":9,"is_corresponding":false},{"id":855581,"name":"Jinlong Lin","orcid":null,"position":0,"is_corresponding":true}],"reference_count":33,"raw_metadata":null,"created_at":"2026-07-19T02:02:16.291892Z","pmid":"39296406","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}