{"doi":"10.13016/m2eurt-0f88","title":"A Generative Approach for Image Registration of Visible-Thermal (VT) Cancer Faces","abstract":"Since thermal imagery offers a unique modality to investigate pain, the U.S. National Institutes of Health (NIH) has collected a large and diverse set of cancer patient facial thermograms for AI-based pain research. However, differing angles from camera capture between thermal and visible sensors has led to misalignment between Visible-Thermal (VT) images. We modernize the classic computer vision task of image registration by applying and modifying a generative alignment algorithm to register VT cancer faces, without the need for a reference or alignment parameters. By registering VT faces, we demonstrate that the quality of thermal images produced in the generative AI downstream task of Visible-to-Thermal (V2T) image translation significantly improves up to 52.5\\%, than without registration. Images in this paper have been approved by the NIH NCI for public dissemination.","journal":"arXiv (Cornell University)","year":2023,"id":410804,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9548,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1191359,"name":"Alexandra Cha","orcid":null,"position":1,"is_corresponding":false},{"id":1190996,"name":"Edward Raff","orcid":"0000-0002-9900-1972","position":2,"is_corresponding":false},{"id":1190997,"name":"Sanjay Purushotham","orcid":"0000-0003-4315-7916","position":3,"is_corresponding":false},{"id":1191360,"name":"Karen Kwok","orcid":null,"position":4,"is_corresponding":false},{"id":1191361,"name":"Mason Rule","orcid":null,"position":5,"is_corresponding":false},{"id":239942,"name":"James L. Gulley","orcid":"0000-0002-6569-2912","position":6,"is_corresponding":false},{"id":1191358,"name":"Catherine Ordun","orcid":null,"position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-19T01:21:38.940853Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}