{"doi":"10.12968/jowc.2022.31.sup10.s41","title":"Combined application of moist exposed burn ointment and maggot therapy in wound healing","abstract":"<jats:sec><jats:title>Objective:</jats:title><jats:p> Hard-to-heal wounds are a global health challenge, and effective treatments are still lacking. Moist exposed burn ointment (MEBO) and maggots are traditional treatments for promoting wound healing. This study was a preliminary exploration of combined maggot therapy and MEBO in the treatment of hard-to-heal wounds. </jats:p></jats:sec><jats:sec><jats:title>Method:</jats:title><jats:p> A coexistence experiment was conducted to determine the survival rates of maggots in MEBO. The maggots were placed in two different existence conditions: one set in MEBO (MEBO group), and another set as the control group (no MEBO) to compare survival rates. Case reports describe the use of the combined application of MEBO and maggots in the treatment of patients with hard-to-heal wounds. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> The coexistence experiment indicated that maggots in the MEBO group had a higher survival rate. From the therapeutic effect of the clinical cases (n=7), the combined application was safe and effective, with all the reported wounds eventually healing. </jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p> Based on the findings of this study, we believe the combined application of MEBO and maggots is a promising way of promoting wound healing. Further studies and clinical trials are needed to elucidate the mechanism of the combined application in promoting wound healing and to more persuasively clarify the therapeutic effect. </jats:p></jats:sec>","journal":"Journal of Wound Care","year":2022,"id":684343,"datarank":0.29188652235829704,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"self_citation_contribution":0.29188652235829704,"citation_network_contribution":0.0,"self_endowment_contribution":0.29188652235829704,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":327043,"name":"Xiaodong Bai","orcid":"0000-0002-6363-2764","position":1,"is_corresponding":false},{"id":1209841,"name":"Deyu Wang","orcid":"0000-0002-4674-3497","position":2,"is_corresponding":false},{"id":1787836,"name":"Qingxin Wang","orcid":null,"position":3,"is_corresponding":false},{"id":1787838,"name":"Liwen Pan","orcid":null,"position":4,"is_corresponding":false},{"id":939965,"name":"Ping He","orcid":"0000-0002-8005-8119","position":5,"is_corresponding":false},{"id":29209,"name":"Ying Gong","orcid":"0000-0001-5987-5344","position":6,"is_corresponding":false},{"id":916833,"name":"Xiaohong Sun","orcid":null,"position":7,"is_corresponding":false},{"id":326614,"name":"Xiaoguang Xu","orcid":"0000-0003-4568-1623","position":8,"is_corresponding":false},{"id":1787839,"name":"Jianzhong Che","orcid":null,"position":9,"is_corresponding":false},{"id":854572,"name":"Shouyu Wang","orcid":"0000-0002-0466-1274","position":10,"is_corresponding":false},{"id":1787835,"name":"Mingzhi Song","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Combined application of moist exposed burn ointment and maggot therapy in wound healing","abstract":"<jats:sec><jats:title>Objective:</jats:title><jats:p> Hard-to-heal wounds are a global health challenge, and effective treatments are still lacking. Moist exposed burn ointment (MEBO) and maggots are traditional treatments for promoting wound healing. This study was a preliminary exploration of combined maggot therapy and MEBO in the treatment of hard-to-heal wounds. </jats:p></jats:sec><jats:sec><jats:title>Method:</jats:title><jats:p> A coexistence experiment was conducted to determine the survival rates of maggots in MEBO. The maggots were placed in two different existence conditions: one set in MEBO (MEBO group), and another set as the control group (no MEBO) to compare survival rates. Case reports describe the use of the combined application of MEBO and maggots in the treatment of patients with hard-to-heal wounds. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> The coexistence experiment indicated that maggots in the MEBO group had a higher survival rate. From the therapeutic effect of the clinical cases (n=7), the combined application was safe and effective, with all the reported wounds eventually healing. </jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p> Based on the findings of this study, we believe the combined application of MEBO and maggots is a promising way of promoting wound healing. Further studies and clinical trials are needed to elucidate the mechanism of the combined application in promoting wound healing and to more persuasively clarify the therapeutic effect. </jats:p></jats:sec>","is_dataset_classified":null,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"36240870","pmcid":null,"openalex_id":"https://openalex.org/W4306247494","authors":[],"funders":[],"total_grants":0,"fwci":0.9307,"citation_percentile":0.74770738,"influential_citations":0,"citation_trend":[{"year":2023,"count":1},{"year":2024,"count":3},{"year":2025,"count":1},{"year":2026,"count":1}],"oa_status":"closed","license":null,"oa_locations":[{"url":"http://www.magonlinelibrary.com/doi/pdf/10.12968/jowc.2022.31.Sup10.S41","host_type":"publisher"},{"url":"https://doi.org/10.12968/jowc.2022.31.sup10.s41","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/36240870","host_type":"repository"}],"fields_of_study":["Forensic Entomology and Diptera Studies","Insect Utilization and Effects","Wound Healing and Treatments"],"mesh_terms":["Animals","Debridement","Humans","Larva","Sitosterols","Wound Healing"],"keywords":["Maggot","Medicine","Wound healing","Burn wound","Surgery","Chronic","Wound","Wound Care","Maggots","Wound Dressing","Maggot Therapy","Mebo","Moist Exposed Burn Ointment","Hard-to-heal"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-18T13:51:24.348332Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}