{"doi":"10.1271/bbb.70081","title":"Evidence for New β1-3 Galactosyltransferase Activity Involved in Biosynthesis of Unusual<i>N</i>-Glycan Harboring T-Antigen in<i>Apis mellifera</i>","abstract":null,"journal":"Bioscience, Biotechnology, and Biochemistry","year":2007,"id":605144,"datarank":0.29188652235829704,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"self_citation_contribution":0.29188652235829704,"citation_network_contribution":0.0,"self_endowment_contribution":0.29188652235829704,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1552994,"name":"Sho SAKAMURA","orcid":null,"position":1,"is_corresponding":false},{"id":1552995,"name":"Takayuki USHIJIMA","orcid":null,"position":2,"is_corresponding":false},{"id":1552996,"name":"Yoichiro HAMA","orcid":null,"position":3,"is_corresponding":false},{"id":1552998,"name":"Hiroyuki KAJIURA","orcid":null,"position":4,"is_corresponding":false},{"id":1553000,"name":"Kazuhito FUJIYAMA","orcid":null,"position":5,"is_corresponding":false},{"id":1553003,"name":"Kiyoshi OKIHARA","orcid":null,"position":6,"is_corresponding":false},{"id":1553005,"name":"Ken HASHIMOTO","orcid":null,"position":7,"is_corresponding":false},{"id":1553007,"name":"Hiroyuki SUGIMOTO","orcid":null,"position":8,"is_corresponding":false},{"id":1553009,"name":"Hideo YAMADA","orcid":null,"position":9,"is_corresponding":false},{"id":1552993,"name":"Yoshinobu KIMURA","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Evidence for New β1-3 Galactosyltransferase Activity Involved in Biosynthesis of Unusual<i>N</i>-Glycan Harboring T-Antigen in<i>Apis mellifera</i>","abstract":"In a previous study (Y. Kimura et al., Biosci. Biotechnol. Biochem., 70, 2583-2587, 2006), we found that new complex type N-glycans harboring Thomsen-Friedenreich antigen (Galbeta1-3GalNAc) unit occur on royal jelly glycoproteins, suggesting the involvement of a new beta1-3galactosyltransferase in the synthesis of the unusual complex type N-glycans. So far, such beta1-3galactosyltransferase activity, which can transfer galactosyl residues with the beta1-3 linkage to beta1-4 GalNAc residues in N-glycan, has not been found among any eucaryotic cells. But using GalNAc(2)GlcNAc(2)Man(3)GlcNAc(2)-PA as acceptor N-glycan, we detected the beta1-3 galactosyltransferase activity in membrane fraction prepared from honeybee cephalic portions. This result indicates that honeybee expresses a unique beta1-3 galactosyltransferase involved in biosynthesis of the unusual N-glycan containing a tumor related antigen in the hypopharyngeal gland.","is_dataset_classified":null,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"17420569","pmcid":null,"openalex_id":"https://openalex.org/W2104808167","authors":[],"funders":[],"total_grants":0,"fwci":0.1257,"citation_percentile":0.51955779,"influential_citations":0,"citation_trend":[{"year":2014,"count":1},{"year":2015,"count":4}],"oa_status":"bronze","license":null,"oa_locations":[{"url":"https://academic.oup.com/bbb/article-pdf/71/4/1111/35114727/bbb1111.pdf","host_type":"journal"},{"url":"https://academic.oup.com/bbb/article-pdf/71/4/1111/35114727/bbb1111.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1271/bbb.70081","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/17420569","host_type":"repository"}],"fields_of_study":["Glycosylation and Glycoproteins Research","Transgenic Plants and Applications","Toxin Mechanisms and Immunotoxins"],"mesh_terms":["Animals","Antigens, Viral, Tumor","Bees","Chromatography, High Pressure Liquid","Escherichia coli","Galactosyltransferases","Gas Chromatography-Mass Spectrometry","Microsomes","Polysaccharides","Recombinant Proteins","Spectrometry, Mass, Electrospray Ionization","Databases, Genetic"],"keywords":["Galactosyltransferase","Glycan","Glycoprotein","Biosynthesis","Antigen","Biochemistry","Glycobiology","Chemistry","Biology","Stereochemistry","Molecular biology","Gene","Enzyme","Genetics"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-30T01:46:39.043525Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}