{"doi":"10.12688/f1000research.126840.2","title":"Gene expression data visualization tool on the o²S²PARC platform","abstract":"<ns4:p> <ns4:bold>Background:</ns4:bold> The identification of differentially expressed genes and their associated biological processes, molecular function, and cellular components are essential for genetic disease studies because they present potential biomarkers and therapeutic targets. </ns4:p> <ns4:p> <ns4:bold>Methods:</ns4:bold> In this study, we developed an o²S²PARC template to instantiate an interactive pipeline for gene expression data visualization, ontological mapping, and statistical evaluation. To demonstrate the tool's usefulness, we performed a case study on a publicly available dataset. </ns4:p> <ns4:p> <ns4:bold>Results:</ns4:bold> The tool enables users to identify the differentially expressed genes (DEGs) and visualize them in a volcano plot format. Ontologies associated with the DEGs are assigned and visualized in barplots. </ns4:p> <ns4:p> <ns4:bold>Conclusions</ns4:bold> : The “Expression data visualization” template is publicly available on the o²S²PARC platform. </ns4:p>","journal":"F1000Research","year":2023,"id":383013,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9609,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":982229,"name":"Mengyuan Ding","orcid":"0000-0002-6009-3873","position":1,"is_corresponding":false},{"id":86415,"name":"Anmol Kiran","orcid":"0000-0003-2680-2303","position":2,"is_corresponding":false},{"id":982228,"name":"Hiba Ben Aribi","orcid":"0000-0001-9547-8725","position":0,"is_corresponding":true}],"reference_count":12,"raw_metadata":null,"created_at":"2026-07-19T01:17:25.158896Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}