{"doi":"10.1242/dev.102103","title":"Plant germline formation: common concepts and developmental flexibility in sexual and asexual reproduction","abstract":"<jats:p>The life cycle of flowering plants alternates between two heteromorphic generations: a diploid sporophytic generation and a haploid gametophytic generation. During the development of the plant reproductive lineages – the germlines – typically, single sporophytic (somatic) cells in the flower become committed to undergo meiosis. The resulting spores subsequently develop into highly polarized and differentiated haploid gametophytes that harbour the gametes. Recent studies have provided insights into the genetic basis and regulatory programs underlying cell specification and the acquisition of reproductive fate during both sexual reproduction and asexual (apomictic) reproduction. As we review here, these recent advances emphasize the importance of transcriptional, translational and post-transcriptional regulation, and the role of epigenetic regulatory pathways and hormonal activity.</jats:p>","journal":"Development","year":2015,"id":18111,"datarank":5.112555141308144,"base_score":5.176149732573829,"endowment":5.176149732573829,"self_citation_contribution":0.7764224598860744,"citation_network_contribution":4.33613268142207,"self_endowment_contribution":0.7764224598860744,"citer_contribution":4.33613268142207,"corpus_percentile":null,"corpus_rank":null,"citation_count":176,"citer_count":145,"citers_with_citation_signal":128,"citers_with_endowment":128,"datacite_reuse_total":25,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":127079,"name":"Marc W. Schmid","orcid":null,"position":1,"is_corresponding":false},{"id":127080,"name":"Ueli Grossniklaus","orcid":null,"position":2,"is_corresponding":false},{"id":127078,"name":"Anja Schmidt","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":5.176149732573829,"endowment":5.176149732573829,"datacite_reuse_total":25,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"25564620","pmcid":null,"openalex_id":"https://openalex.org/W1998874710","authors":[],"funders":[{"funder_name":"European Commission","grant_id":"250358","title":"Mechanisms of Epigenetic regulation in Development, Evolution and Adaptation"},{"funder_name":"Swiss National Science Foundation","grant_id":"141245","title":"The Genetic and Molecular Basis of Gametogenesis and Maternal Effects in 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Reproductive Biology","Plant Molecular Biology Research","Plant tissue culture and regeneration","Biology","Medicine","Environmental Science","0301 basic medicine","0303 health sciences","03 medical and health sciences","Cell Lineage","Cell Polarity","Epigenesis, Genetic","Gametogenesis","Gene Expression Regulation, Developmental","Gene Expression Regulation, Plant","Germ Cells, Plant","Meiosis","Plant Development","Plants","Reproduction"],"mesh_terms":["Gametogenesis","Meiosis","Plants","Reproduction","Cell Polarity","Gene Expression Regulation, Plant","Gene Expression Regulation, Developmental","Cell Lineage","Epigenesis, Genetic","Germ Cells, Plant","Plant Development"],"keywords":["Biology","Apomixis","Sexual reproduction","Asexual reproduction","Germline","Ploidy","Meiosis","Evolutionary biology","Gametophyte","Genetics","Plant reproduction","Somatic cell","Epigenetics","Zygote","Gene","Pollen","Botany","Pollination","Gene regulation","Polarity","Cell Fate Acquisition","Germline 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