{"doi":"10.1210/jcem-49-3-435","title":"Indirect Immunofluorescent Localization of Prolactin to the Cytoplasm of Decidua and Trophoblast Cells in Human Placental Membranes at Term","abstract":null,"journal":"The Journal of Clinical Endocrinology & Metabolism","year":1979,"id":623830,"datarank":4.3799651661846095,"base_score":3.784189633918261,"endowment":3.784189633918261,"self_citation_contribution":0.5676284450877392,"citation_network_contribution":3.81233672109687,"self_endowment_contribution":0.5676284450877392,"citer_contribution":3.81233672109687,"corpus_percentile":null,"corpus_rank":null,"citation_count":43,"citer_count":42,"citers_with_citation_signal":40,"citers_with_endowment":40,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1612409,"name":"LYNN WILEY","orcid":null,"position":1,"is_corresponding":false},{"id":1612411,"name":"ALAN D. ROGOL","orcid":null,"position":2,"is_corresponding":false},{"id":1612407,"name":"LYNN T. FRAME","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Indirect Immunofluorescent Localization of Prolactin to the Cytoplasm of Decidua and Trophoblast Cells in Human Placental Membranes at Term","abstract":"An indirect immunofluorescent technique was used to determine the localization of cytoplasmic human PRL (hPRL) in fresh and incubated human placental membranes at term. In both fresh and 8-h incubated samples of amnion, amniochorion decidua, or chorion decidua obtained from three placentas, we found specific reproducible localization of hPRL to the cytoplasm of decidua and trophoblast cells. The decidua cells appeared to be the most intensely fluorescent. No specific hPRL immunofluorescence was noted in the amniotic epithelium of fresh or incubated samples of amnion and amniochorion decidua. These data suggest that the trophoblast decidua cell layer is the site of PRL localization and possibly synthesis in placental membranes at term and may be the origin of amniotic fluid PRL in humans.","is_dataset_classified":null,"base_score":3.784189633918261,"endowment":3.784189633918261,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"381323","pmcid":null,"openalex_id":"https://openalex.org/W1983001373","authors":[],"funders":[],"total_grants":0,"fwci":2.7351,"citation_percentile":0.90451969,"influential_citations":0,"citation_trend":[{"year":2017,"count":1},{"year":2019,"count":1}],"oa_status":"closed","license":null,"oa_locations":[{"url":"http://academic.oup.com/jcem/article-pdf/49/3/435/10514146/jcem0435.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1210/jcem-49-3-435","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/381323","host_type":"repository"}],"fields_of_study":["Reproductive System and Pregnancy","Pregnancy and preeclampsia studies","Preterm Birth and Chorioamnionitis","Cytoplasm","Decidua","Female","Fluorescent Antibody Technique","Humans","Labor, Obstetric","Pregnancy","Prolactin","Trophoblasts"],"mesh_terms":["Cytoplasm","Decidua","Female","Fluorescent Antibody Technique","Humans","Labor, Obstetric","Pregnancy","Prolactin","Trophoblasts"],"keywords":["Decidua","Amnion","Biology","Trophoblast","Fetal membrane","Placenta","Cytoplasm","Decidual cells","Prolactin","Andrology","Immunofluorescence","Amniotic fluid","Endocrinology","Chorionic villi","Internal medicine","Fetus","Cell biology","Pregnancy","Immunology","Hormone","Antibody"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-04T01:32:52.250100Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}