{"doi":"10.1200/cci.19.00124","title":"Enhancing the Quality of Hierarchic Relations in the National Cancer Institute Thesaurus to Enable Faceted Query of Cancer Registry Data","abstract":"PURPOSE: To audit and improve the completeness of the hierarchic (or is-a) relations of the National Cancer Institute (NCI) Thesaurus to support its role as a faceted system for querying cancer registry data. METHODS: We performed quality auditing of the 19.01d version of the NCI Thesaurus. Our hybrid auditing method consisted of three main steps: computing nonlattice subgraphs, constructing lexical features for concepts in each subgraph, and performing subsumption reasoning with each subgraph to automatically suggest potentially missing is-a relations. RESULTS: A total of 9,512 nonlattice subgraphs were obtained. Our method identified 925 potentially missing is-a relations in 441 nonlattice subgraphs; 72 of 176 reviewed samples were confirmed as valid missing is-a relations and have been incorporated in the newer versions of the NCI Thesaurus. CONCLUSION: Autosuggested changes resulting from our auditing method can improve the structural organization of the NCI Thesaurus in supporting its new role for faceted query.","journal":"JCO Clinical Cancer Informatics","year":2020,"id":111717,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.8027,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":453371,"name":"Rashmie Abeysinghe","orcid":"0000-0001-9297-9540","position":1,"is_corresponding":false},{"id":441640,"name":"Fengbo Zheng","orcid":"0000-0001-5902-0186","position":2,"is_corresponding":false},{"id":428366,"name":"Shiqiang Tao","orcid":"0000-0003-1515-3184","position":3,"is_corresponding":false},{"id":428367,"name":"Ningzhou Zeng","orcid":"0000-0001-9807-0004","position":4,"is_corresponding":false},{"id":357613,"name":"Isaac Hands","orcid":null,"position":5,"is_corresponding":false},{"id":85407,"name":"Eric B. Durbin","orcid":"0000-0002-5600-7645","position":6,"is_corresponding":false},{"id":95768,"name":"Lori L Whiteman","orcid":"0000-0001-6475-1637","position":7,"is_corresponding":false},{"id":95750,"name":"Lyubov Remennik","orcid":null,"position":8,"is_corresponding":false},{"id":95755,"name":"Nicholas Sioutos","orcid":null,"position":9,"is_corresponding":false},{"id":428368,"name":"Guo‐Qiang Zhang","orcid":"0000-0002-3663-1109","position":10,"is_corresponding":false},{"id":110439,"name":"Licong Cui","orcid":"0000-0001-5549-8780","position":0,"is_corresponding":true}],"reference_count":10,"raw_metadata":null,"created_at":"2026-07-18T23:13:09.353152Z","pmid":"32374632","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}