{"doi":"10.1192/bjp.184.5.386","title":"Global burden of depressive disorders in the year 2000","abstract":"<jats:sec><jats:title>Background</jats:title><jats:p>The initial Global Burden of Disease study found that depression was the fourth leading cause of disease burden, accounting for 3.7% of total disability adjusted life years (DALYs) in the world in 1990.</jats:p></jats:sec><jats:sec><jats:title>Aims</jats:title><jats:p>To present the new estimates of depression burden for the year 2000.</jats:p></jats:sec><jats:sec><jats:title>Method</jats:title><jats:p>DALYs for depressive disorders in each world region were calculated, based on new estimates of mortality, prevalence, incidence, average age at onset, duration and disability severity.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Depression is the fourth leading cause of disease burden, accounting for 4.4% of total DALYs in the year 2000, and it causes the largest amount of non-fatal burden, accounting for almost 12% of all total years lived with disability worldwide.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>These data on the burden of depression worldwide represent a major public health problem that affects patients and society.</jats:p></jats:sec>","journal":"British Journal of Psychiatry","year":2004,"id":588897,"datarank":17.505986362611925,"base_score":7.462789157412448,"endowment":7.462789157412448,"self_citation_contribution":1.1194183736118675,"citation_network_contribution":16.386567989000056,"self_endowment_contribution":1.1194183736118675,"citer_contribution":16.386567989000056,"corpus_percentile":null,"corpus_rank":null,"citation_count":1741,"citer_count":200,"citers_with_citation_signal":200,"citers_with_endowment":200,"datacite_reuse_total":6,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1506698,"name":"J. L. Ayuso-Mateos","orcid":null,"position":1,"is_corresponding":false},{"id":76416,"name":"S. Chatterji","orcid":"0000-0002-0197-366X","position":2,"is_corresponding":false},{"id":1506699,"name":"C. Mathers","orcid":null,"position":3,"is_corresponding":false},{"id":1506700,"name":"C. J. L. Murray","orcid":null,"position":4,"is_corresponding":false},{"id":1506697,"name":"T. B. Üstün","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Global burden of depressive disorders in the year 2000","abstract":"<jats:sec><jats:title>Background</jats:title><jats:p>The initial Global Burden of Disease study found that depression was the fourth leading cause of disease burden, accounting for 3.7% of total disability adjusted life years (DALYs) in the world in 1990.</jats:p></jats:sec><jats:sec><jats:title>Aims</jats:title><jats:p>To present the new estimates of depression burden for the year 2000.</jats:p></jats:sec><jats:sec><jats:title>Method</jats:title><jats:p>DALYs for depressive disorders in each world region were calculated, based on new estimates of mortality, prevalence, incidence, average age at onset, duration and disability severity.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Depression is the fourth leading cause of disease burden, accounting for 4.4% of total DALYs in the year 2000, and it causes the largest amount of non-fatal burden, accounting for almost 12% of all total years lived with disability worldwide.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>These data on the burden of depression worldwide represent a major public health problem that affects patients and society.</jats:p></jats:sec>","is_dataset_classified":null,"base_score":7.462789157412448,"endowment":7.462789157412448,"datacite_reuse_total":6,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"15123501","pmcid":null,"openalex_id":"https://openalex.org/W2145151017","authors":[],"funders":[{"funder_name":"NIMH NIH HHS","grant_id":"MH35883","title":null}],"total_grants":1,"fwci":66.734,"citation_percentile":0.99958417,"influential_citations":0,"citation_trend":[{"year":2012,"count":112},{"year":2013,"count":135},{"year":2014,"count":124},{"year":2015,"count":120},{"year":2016,"count":89},{"year":2017,"count":127},{"year":2018,"count":80},{"year":2019,"count":67},{"year":2020,"count":61},{"year":2021,"count":52},{"year":2022,"count":46},{"year":2023,"count":55},{"year":2024,"count":25},{"year":2025,"count":17},{"year":2026,"count":7}],"oa_status":"bronze","license":"https://www.cambridge.org/core/terms","oa_locations":[{"url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/5598D370DE4F8FB2FDFC71CC85E1B159/S0007125000163883a.pdf/div-class-title-global-burden-of-depressive-disorders-in-the-year-2000-div.pdf","host_type":"journal"},{"url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/5598D370DE4F8FB2FDFC71CC85E1B159/S0007125000163883a.pdf/div-class-title-global-burden-of-depressive-disorders-in-the-year-2000-div.pdf","host_type":"publisher"},{"url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0007125000163883","host_type":"publisher"},{"url":"https://doi.org/10.1192/bjp.184.5.386","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/15123501","host_type":"repository"}],"fields_of_study":["Mental Health Treatment and Access","Treatment of Major Depression","Child and Adolescent Psychosocial and Emotional Development","Adult","Cost of Illness","Depressive Disorder","Disability Evaluation","Female","Global Health","Humans","Incidence","Male","Prevalence","Public Health","Quality-Adjusted Life Years"],"mesh_terms":["Adult","Depressive Disorder","Disability Evaluation","Female","Humans","Male","Public Health","Global Health","Incidence","Prevalence","Cost of Illness","Quality-Adjusted Life Years"],"keywords":["Burden of disease","Depression (economics)","Disease burden","Medicine","Incidence (geometry)","Public health","Years of potential life lost","Disease","Quality-adjusted life year","Environmental health","Demography","Psychiatry","Life expectancy","Cost effectiveness","Population"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[{"doi":"10.6084/m9.figshare.12096774.v1","title":"Additional file 1 of Cost analysis of depression using the national insurance system in South Korea: a comparison of depression and treatment-resistant depression","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.12096774","title":"Additional file 1 of Cost analysis of depression using the national insurance system in South Korea: a comparison of depression and treatment-resistant depression","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.14253447.v1","title":"Additional file 1 of Workplace factors associated with mental health of healthcare workers during the COVID-19 pandemic: an international cross-sectional study","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.14253447","title":"Additional file 1 of Workplace factors associated with mental health of healthcare workers during the COVID-19 pandemic: an international cross-sectional study","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.15178631.v1","title":"Additional file 1 of Cost-effectiveness of a stepped care program to prevent depression among primary care patients with diabetes mellitus type 2 and/or coronary heart disease and subthreshold depression in comparison with usual care","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.15178631","title":"Additional file 1 of Cost-effectiveness of a stepped care program to prevent depression among primary care patients with diabetes mellitus type 2 and/or coronary heart disease and subthreshold depression in comparison with usual care","publisher":"figshare","resource_type":"JournalArticle"}],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-23T01:15:24.534526Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}