{"doi":"10.1186/s12944-017-0617-0","title":"Effects of 12-week supplementation of marine Omega-3 PUFA-based formulation Omega3Q10 in older adults with prehypertension and/or elevated blood cholesterol","abstract":null,"journal":"Lipids in Health and Disease","year":2017,"id":678432,"datarank":0.5289540786924243,"base_score":3.5263605246161616,"endowment":3.5263605246161616,"self_citation_contribution":0.5289540786924243,"citation_network_contribution":0.0,"self_endowment_contribution":0.5289540786924243,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":33,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1599314,"name":"Guoqiang Xing","orcid":"0000-0002-4706-3063","position":1,"is_corresponding":false},{"id":1772584,"name":"Jingfen Zhu","orcid":null,"position":2,"is_corresponding":false},{"id":696759,"name":"Shuxian Zhang","orcid":"0000-0001-8619-1554","position":3,"is_corresponding":false},{"id":79253,"name":"Yong Cai","orcid":"0000-0001-9849-0658","position":4,"is_corresponding":false},{"id":1772585,"name":"Donghua Li","orcid":null,"position":5,"is_corresponding":false},{"id":924804,"name":"Gang Xu","orcid":"0009-0001-7379-7167","position":6,"is_corresponding":false},{"id":1772586,"name":"Evan Xing","orcid":null,"position":7,"is_corresponding":false},{"id":414470,"name":"Jianyu Rao","orcid":"0000-0002-8188-1780","position":8,"is_corresponding":false},{"id":1327666,"name":"Rong Shi","orcid":"0000-0001-8494-900X","position":9,"is_corresponding":false},{"id":437316,"name":"Tian Shen","orcid":"0000-0001-7064-7051","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Effects of 12-week supplementation of marine Omega-3 PUFA-based formulation Omega3Q10 in older adults with prehypertension and/or elevated blood cholesterol.","abstract":"<h4>Backgrounds</h4>To study the effects of supplementation of a marine omega-3 poly-unsaturated fatty acids (n3-PUFA) formulation (Omega3Q10) in older adults with hypertension and/or hypercholesterolemia.<h4>Methods</h4>A total of 97 people were enrolled to receive 12-week supplementation of either Omega3Q10 (n = 48) or soybean oil (n = 49). Total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and hypertension-related symptoms were determined before and after the supplementation.<h4>Results</h4>There were no baseline differences between the two groups. Omega3Q10 supplementation significantly reduced diastolic blood pressure (DBP) (from 81.6 ± 5.3 mmHg to 79.3 ± 5.2 mmHg, P < 0.05). Blood concentrations of TC and LDL-C decreased significantly and blood HDL-C level increased significantly after 12 weeks of Omega3Q10 (5.5 ± 0.7 vs. 5.3 ± 0.5, P < 0.05; 3.7 ± 0.8 vs. 3.3 ± 0.6, P < 0.05; 1.2 ± 0.6 vs. 1.3 ± 0.5, P < 0.05, respectively) and soybean oil supplementation (5.7 ± 0.8 vs. 5.6 ± 0.7, P < 0.05; 3.6 ± 0.7 vs. 3.4 ± 0.8, P < 0.05; 1.0 ± 0.8 vs. 1.2 ± 0.7, P < 0.05, respectively) but no group differences were found. A significantly greater proportion of the people in the Omega3Q10 group became free from headache and palpitations & chest tightness symptoms after the 12-week supplementation compared to that of the soybean oil group (95.5% vs. 71.4%, P < 0.01; 95.8 vs. 75.5%, P < 0.01, respectively).<h4>Conclusion</h4>12-week supplementation of Fish oil-based PUFA appear to be more effective in improving DBP and hypertension-related symptoms than soybean oil in old adults with hypertension and hypercholesterolemia although both supplementation improved TC, LDL-C and HDL-C concentrations.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"29282085","pmcid":"PMC5745982","openalex_id":null,"authors":[],"funders":[{"funder_name":"Shanghai Key Discipline Construction Project in Public Health","grant_id":"15GWZK1002","title":null},{"funder_name":"the Social Cognitive and Behavioral Sciences Program of Shanghai Jiao Tong University","grant_id":"14JCRY03","title":null},{"funder_name":"National Natural Science Foundation of China","grant_id":"7163187","title":null},{"funder_name":"DRM Resources","grant_id":"","title":null}],"total_grants":4,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://lipidworld.biomedcentral.com/counter/pdf/10.1186/s12944-017-0617-0","host_type":"publisher"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5745982","host_type":"repository"},{"url":"https://doaj.org/article/14c04165140a4f93be5bc17ca7ea1191","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC5745982","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC5745982?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":[],"mesh_terms":["Humans","Hypercholesterolemia","Fatty Acids, Omega-3","Soybean Oil","Triglycerides","Double-Blind Method","Blood Pressure","Time Factors","Dietary Supplements","Aged","Aged, 80 and over","Middle Aged","Female","Male","Lipid Metabolism","Cholesterol, LDL","Cholesterol, HDL","Prehypertension"],"keywords":["Soybean oil","Blood Pressures, Dyslipidemia, Old Adults","Fish Oil-derived Pufa"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-17T05:25:18.752350Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}