{"doi":"10.1186/s12875-025-03030-6","title":"Accelerating the translation of findings from the MoTrPAC study to benefit clinical care: a qualitative analysis","abstract":"BACKGROUND: The Molecular Transducers of Physical Activity Consortium (MoTrPAC) is a large-scale research study aimed at elucidating the effects of exercise training on the molecular mechanisms underlying the health benefits of exercise and physical activity. To take a first step toward achieving a goal of rapid dissemination, a qualitative analysis among frontline clinicians was conducted to identify the perceived clinical relevance of exercise research, MoTrPAC discoveries, and optimal ways to disseminate these results to key stakeholders. METHODS: A convenience sample of 12 clinicians in internal medicine, family medicine, and emergency medicine agreed to participate in one-on-one interviews. Interviews were conducted over the phone by a member of the Wake Forest Qualitative and Patient-Reported Outcomes (Q-PRO) Shared Resource. Transcripts were stored and coded in ATLAS.ti version 24 software. Two Q-PRO members developed code summaries, which were synthesized into themes and organized using principles of reflexive thematic analysis. RESULTS: Clinicians (n = 12) were predominantly male (n = 7), non-Hispanic White (n = 5), located in California (n = 10), and practiced in a Primary Care/Family Medicine setting (n = 6). Clinicians reported underuse of exercise testing due to provider-level and patient-level barriers. While they valued exercise research, they emphasized the need for clear, practical takeaways and preferred direct dissemination strategies. CONCLUSIONS: These interviews highlighted the variable nature of exercise research dissemination and implementation and are the first steps toward shaping the dissemination of valuable scientific discoveries from the MoTrPAC study.","journal":"BMC Primary Care","year":2025,"id":579194,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9176,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1448360,"name":"Kandice R. Lacci‐Reilly","orcid":"0000-0001-5889-4340","position":1,"is_corresponding":false},{"id":1394057,"name":"Aylin A. Aguilar","orcid":"0009-0009-4925-1015","position":2,"is_corresponding":false},{"id":227149,"name":"Jerome L. Fleg","orcid":"0000-0002-7211-5603","position":3,"is_corresponding":false},{"id":16813,"name":"Stephanie M. George","orcid":"0000-0002-6783-139X","position":4,"is_corresponding":false},{"id":235344,"name":"Joseph A. Houmard","orcid":"0000-0003-3682-5410","position":5,"is_corresponding":false},{"id":235342,"name":"Kim M. Huffman","orcid":"0000-0003-4708-4734","position":6,"is_corresponding":false},{"id":235349,"name":"Neil M. Johannsen","orcid":"0000-0003-4905-4491","position":7,"is_corresponding":false},{"id":536804,"name":"Daniel H. Katz","orcid":"0000-0001-7237-8502","position":8,"is_corresponding":false},{"id":367844,"name":"Julia H. Narendra","orcid":null,"position":9,"is_corresponding":false},{"id":235321,"name":"Shlomit Radom‐Aizik","orcid":"0009-0004-4023-7026","position":10,"is_corresponding":false},{"id":235346,"name":"Lauren M. Sparks","orcid":"0000-0002-8724-6016","position":11,"is_corresponding":false},{"id":4312,"name":"Ashley Xia","orcid":"0000-0002-9534-8506","position":12,"is_corresponding":false},{"id":38137,"name":"Dan M. Cooper","orcid":"0000-0003-4022-0043","position":13,"is_corresponding":false},{"id":725975,"name":"Katherine A. Collins","orcid":"0000-0001-9712-8980","position":0,"is_corresponding":true}],"reference_count":34,"raw_metadata":null,"created_at":"2026-07-19T02:58:30.282164Z","pmid":"41145998","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}