{"doi":"10.1177/19458924221124692","title":"Profiles of Odorant Specific Performance in Olfactory Testing","abstract":"BACKGROUND: Olfactory dysfunction (OD) can occur from a variety of etiologies. However, there are few reports examining whether varying etiologies have unique profiles of psychophysical testing that may provide insight into the pathophysiology of OD. METHODS: Adults with chronic rhinosinusitis with and without nasal polyps (CRSwNP/CRSsNP) and healthy control adults with no sinus complaints underwent olfactory assessment with Sniffin' Sticks. Profiles of identification and discrimination were compared between CRS and non-CRS subjects across the spectrum of OD. RESULTS: Normosmics with or without CRS identified apple, pineapple, and turpentine less frequently than expected (range 52%-68% correct). Hyposmics with CRS correctly identified orange more frequently than control hyposmics (83%-93% vs 68% for controls) with similar findings for rose. Hyposmics of all cohorts were unable to identify apple (26%). Discrimination profiles were similar across the spectrum of OD and between diagnostic groups. CONCLUSIONS: Identification and discrimination rates of specific odorants may provide unique information regarding the etiology of OD, however psychophysical testing is a complex interplay of olfactory and trigeminal function, the strength of target odorant, distractor choices, and familiarity with odorants.","journal":"American Journal of Rhinology and Allergy","year":2022,"id":293239,"datarank":0.16479184330021646,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"self_citation_contribution":0.16479184330021646,"citation_network_contribution":0.0,"self_endowment_contribution":0.16479184330021646,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9577,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":371307,"name":"Zachary M. Soler","orcid":"0000-0002-4304-595X","position":1,"is_corresponding":false},{"id":371309,"name":"Jess C. Mace","orcid":"0000-0001-5009-3426","position":2,"is_corresponding":false},{"id":932959,"name":"Nyssa Fox Farrell","orcid":"0000-0003-1510-4008","position":3,"is_corresponding":false},{"id":596035,"name":"Ryan Rimmer","orcid":"0000-0002-9010-8183","position":4,"is_corresponding":false},{"id":417728,"name":"Jeremiah A. Alt","orcid":"0000-0003-0560-5028","position":5,"is_corresponding":false},{"id":298602,"name":"Vijay R. Ramakrishnan","orcid":"0000-0003-2748-0705","position":6,"is_corresponding":false},{"id":336425,"name":"Thomas S. Edwards","orcid":"0000-0002-6290-9506","position":7,"is_corresponding":false},{"id":348699,"name":"Timothy L. Smith","orcid":"0000-0002-6424-7083","position":8,"is_corresponding":false},{"id":348698,"name":"Rodney J. Schlosser","orcid":"0000-0001-6480-0275","position":0,"is_corresponding":true}],"reference_count":4,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T00:30:50.076284Z","pmid":"36069003","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}