{"doi":"10.1177/19345798241308474","title":"Neighborhood deprivation and association with 18-month neurodevelopmental impairment of preterm infants born in a dense urban setting","abstract":"Background Neighborhood adversity’s impact on 18-month neurodevelopmental impairment (NDI) is not well-described. The aim of our study was to determine whether area deprivation index (ADI), a measure of neighborhood socioeconomic disadvantage, at birth is associated with 18-month NDI of preterm infants born in dense urban setting. Methods A retrospective case-cohort study was performed in infants born at 23–32 weeks gestational age (GA) with birth weight (BW) ≤1250 g between 2013 and 2017 and evaluated for NDI at 18-month corrected age (CA). Socioeconomic deprivation was computed geospatially using subject addresses that were mapped to national ADI rankings. Subjects were categorized as low (<26 th percentile) or high (26–100 th percentile) ADI neighborhoods and with/without NDI if any of Bayley-III cognition, language, or motor composite scores were <70. The relationship between ADI and NDI was analyzed using logistic regression adjusted for GA and BW and group comparisons were made. Results Data were available in 119 patients (GA = 27.2 ± 2.2 weeks, BW = 870 ± 246 g). Children with NDI at 18-month CA were born at an earlier GA ( p < .001) with lower BW ( p < .03) and to mothers living in high ADI neighborhoods ( p < .02). Patients from lower ADI neighborhoods at birth had higher Bayley-III cognition ( p < .0001), language ( p < .005), and motor ( p = .03) composite scores at 18-month CA. Cognition ( p < .01), language ( p < .003) and motor ( p < .03) composite scores decreased with increasing ADI percentiles. Conclusions Among infants born 23–32 weeks GA in a dense urban setting, ADI at birth is associated with NDI at 18 months with lower cognitive, language, and motor scores in preterm infants from higher ADI neighborhoods.","journal":"Journal of Neonatal-Perinatal Medicine","year":2024,"id":451160,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.8758,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1189154,"name":"Faith Kim","orcid":"0000-0002-0344-0613","position":1,"is_corresponding":false},{"id":471658,"name":"Joseph R. Isler","orcid":"0000-0001-5814-3838","position":2,"is_corresponding":false},{"id":521320,"name":"Rakesh Sahni","orcid":null,"position":3,"is_corresponding":false},{"id":1272142,"name":"Prateek V Sahni","orcid":"0000-0003-1466-0571","position":0,"is_corresponding":true}],"reference_count":36,"raw_metadata":null,"created_at":"2026-07-19T02:02:41.417944Z","pmid":"40016982","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}