{"doi":"10.1177/1076029617705727","title":"Changes in Platelet Count and Size Indices in Adolescent Patients With Anorexia Nervosa","abstract":"<jats:p>The significance of platelet size indices has not been widely analyzed in anorexia nervosa (AN). It seems important to get more knowledge on the easily available indices of platelet function obtained by routine complete blood count analysis in patients with AN. We analyzed platelet count (PLT), platelet distribution width (PDW), and mean platelet volume using an automated blood cell counter in 25 females with AN and healthy age- and gender-matched nonatopic controls. Mean PLT was significantly lower in patients with AN than in the control group. Platelet distribution width values in patients with AN were significantly higher than those in the controls. Platelet distribution width values significantly correlated with the disease duration and rate of body weight loss in the anorectic patients. Anorexia nervosa in adolescents is associated with a decrease in PLT along with an increased PDW, which may be an indicator of dysregulated thrombopoiesis.</jats:p>","journal":"Clinical and Applied Thrombosis/Hemostasis","year":2017,"id":615049,"datarank":0.31191623125197543,"base_score":2.0794415416798357,"endowment":2.0794415416798357,"self_citation_contribution":0.31191623125197543,"citation_network_contribution":0.0,"self_endowment_contribution":0.31191623125197543,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":7,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1585067,"name":"Żaneta Malczyk","orcid":null,"position":1,"is_corresponding":false},{"id":1585069,"name":"Agnieszka Szymlak","orcid":null,"position":2,"is_corresponding":false},{"id":1585070,"name":"Agata Mikołajczak","orcid":null,"position":3,"is_corresponding":false},{"id":1585071,"name":"Katarzyna Ziora","orcid":null,"position":4,"is_corresponding":false},{"id":1585072,"name":"Jacek Zamlynski","orcid":null,"position":5,"is_corresponding":false},{"id":1328790,"name":"Edyta Machura","orcid":"0000-0001-7163-9002","position":6,"is_corresponding":false},{"id":1585073,"name":"Piotr Zajac","orcid":null,"position":7,"is_corresponding":false},{"id":1585074,"name":"Bogdan Koczy","orcid":null,"position":8,"is_corresponding":false},{"id":1585075,"name":"Alicja Kasperska-Zajac","orcid":null,"position":9,"is_corresponding":false},{"id":1585065,"name":"Joanna Oświęcimska","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Changes in Platelet Count and Size Indices in Adolescent Patients With Anorexia Nervosa","abstract":"<jats:p>The significance of platelet size indices has not been widely analyzed in anorexia nervosa (AN). It seems important to get more knowledge on the easily available indices of platelet function obtained by routine complete blood count analysis in patients with AN. We analyzed platelet count (PLT), platelet distribution width (PDW), and mean platelet volume using an automated blood cell counter in 25 females with AN and healthy age- and gender-matched nonatopic controls. Mean PLT was significantly lower in patients with AN than in the control group. Platelet distribution width values in patients with AN were significantly higher than those in the controls. Platelet distribution width values significantly correlated with the disease duration and rate of body weight loss in the anorectic patients. Anorexia nervosa in adolescents is associated with a decrease in PLT along with an increased PDW, which may be an indicator of dysregulated thrombopoiesis.</jats:p>","is_dataset_classified":null,"base_score":2.0794415416798357,"endowment":2.0794415416798357,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"28449596","pmcid":null,"openalex_id":"https://openalex.org/W2608464882","authors":[],"funders":[],"total_grants":0,"fwci":0.3162,"citation_percentile":0.66168176,"influential_citations":0,"citation_trend":[{"year":2019,"count":1},{"year":2021,"count":2},{"year":2023,"count":1},{"year":2024,"count":2},{"year":2025,"count":1}],"oa_status":"closed","license":"http://journals.sagepub.com/page/policies/text-and-data-mining-license","oa_locations":[{"url":"http://journals.sagepub.com/doi/pdf/10.1177/1076029617705727","host_type":"publisher"},{"url":"http://journals.sagepub.com/doi/full-xml/10.1177/1076029617705727","host_type":"publisher"},{"url":"https://doi.org/10.1177/1076029617705727","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/28449596","host_type":"repository"}],"fields_of_study":["Eating Disorders and Behaviors","Obesity, Physical Activity, Diet","Cardiovascular Disease and Adiposity"],"mesh_terms":["Adolescent","Anorexia Nervosa","Blood Platelets","Female","Humans","Platelet Count","Weight Loss","Case-Control Studies","Cell Shape","Mean Platelet Volume"],"keywords":["Mean platelet volume","Platelet","Thrombopoiesis","Anorexia nervosa","Internal medicine","Anorectic","Medicine","Blood cell","Gastroenterology","Endocrinology","Body weight","Eating disorders","Biology","Psychiatry","Haematopoiesis","Platelet count","Platelet Distribution Width","Platelet Indices"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-02T18:42:07.971416Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}