{"doi":"10.1177/107424840100600311","title":"HRCT Findings of Amiodarone Pulmonary Toxicity: Clinical and Radiologic Regression","abstract":"<jats:p>Amiodarone is an antiarrhythmic drug that can cause interstitial pneumonitis leading to pulmonary fibrosis. A 62-year-old man suffering from atrial fibrillation and recurrent dyspnea was treated with amiodarone. After 15 months of treatment, HRCT revealed bilateral interstitial and alveolar opacifications with high-attenuating pleural-parenchymal consolidations, suggesting amiodarone induced pneumonitis. Three months after cessation of amiodarone treatment, HRCT shows complete regression of pneumonitis. Amiodarone pneumonitis can be misinterpreted and mistreated in patients with further underlying diseases. The present case report demonstrates the diagnostic value of HRCT in the diagnosis of interstitial pneumonitis.</jats:p>","journal":"Journal of Cardiovascular Pharmacology and Therapeutics","year":2001,"id":683622,"datarank":0.37273599746820013,"base_score":2.4849066497880004,"endowment":2.4849066497880004,"self_citation_contribution":0.37273599746820013,"citation_network_contribution":0.0,"self_endowment_contribution":0.37273599746820013,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":11,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1785877,"name":"Philip May","orcid":null,"position":1,"is_corresponding":false},{"id":1785878,"name":"Jens-Albrecht Koch","orcid":null,"position":2,"is_corresponding":false},{"id":128638,"name":"Gerd Hetzel","orcid":null,"position":3,"is_corresponding":false},{"id":1785879,"name":"Peter Heering","orcid":null,"position":4,"is_corresponding":false},{"id":1785880,"name":"Ulrich Mödder","orcid":null,"position":5,"is_corresponding":false},{"id":1785876,"name":"Ludger Wilhelm Poll","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"HRCT Findings of Amiodarone Pulmonary Toxicity: Clinical and Radiologic Regression","abstract":"<jats:p>Amiodarone is an antiarrhythmic drug that can cause interstitial pneumonitis leading to pulmonary fibrosis. A 62-year-old man suffering from atrial fibrillation and recurrent dyspnea was treated with amiodarone. After 15 months of treatment, HRCT revealed bilateral interstitial and alveolar opacifications with high-attenuating pleural-parenchymal consolidations, suggesting amiodarone induced pneumonitis. Three months after cessation of amiodarone treatment, HRCT shows complete regression of pneumonitis. Amiodarone pneumonitis can be misinterpreted and mistreated in patients with further underlying diseases. The present case report demonstrates the diagnostic value of HRCT in the diagnosis of interstitial pneumonitis.</jats:p>","is_dataset_classified":null,"base_score":2.4849066497880004,"endowment":2.4849066497880004,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"11584337","pmcid":null,"openalex_id":"https://openalex.org/W2029292534","authors":[],"funders":[],"total_grants":0,"fwci":0.5249,"citation_percentile":0.67304358,"influential_citations":0,"citation_trend":[{"year":2012,"count":1},{"year":2014,"count":1},{"year":2019,"count":1},{"year":2025,"count":1}],"oa_status":"closed","license":"https://journals.sagepub.com/page/policies/text-and-data-mining-license","oa_locations":[{"url":"https://journals.sagepub.com/doi/pdf/10.1177/107424840100600311","host_type":"publisher"},{"url":"https://doi.org/10.1177/107424840100600311","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/11584337","host_type":"repository"}],"fields_of_study":["Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","Pneumonia and Respiratory Infections","Cardiac electrophysiology and arrhythmias","Amiodarone","Anti-Arrhythmia Agents","Humans","Lung Diseases, Interstitial","Male","Middle Aged","Respiratory Function Tests","Tomography, X-Ray Computed"],"mesh_terms":["Amiodarone","Anti-Arrhythmia Agents","Humans","Male","Middle Aged","Respiratory Function Tests","Tomography, X-Ray Computed","Lung Diseases, Interstitial"],"keywords":["Amiodarone","Medicine","Pulmonary toxicity","Pneumonitis","Hypersensitivity pneumonitis","Atrial fibrillation","Interstitial pneumonitis","Pulmonary fibrosis","Interstitial lung disease","Cardiology","Lung","Internal medicine","Radiology","Usual interstitial pneumonia","Respiratory disease"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-18T11:41:27.257992Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}