{"doi":"10.1177/09564624231185622","title":"Lessons learned from U.S. rapid antiretroviral therapy initiation programs","abstract":"BACKGROUND: Rapid antiretroviral therapy initiation (R-ART) for treatment of HIV has been recommended since 2017, however it has not been adopted widely across the US. PURPOSE: The study purpose was to understand facilitators and barriers to R-ART implementation in the U.S. RESEARCH DESIGN: This was a qualitative design involving semi-structured interviews. STUDY SAMPLE: The study sample was comprised of the medical leadership of nine US HIV clinics that were early implementers of R-ART. DATA COLLECTION AND ANALYSIS: In-depth, semi-structured interviews were performed. The Consolidated Framework for Implementation Research (CFIR) was used to guide thematic analysis. RESULTS: We identified three main content areas: strong scientific rationale for R-ART, buy-in from multiple key stakeholders, and the condensed timeline of R-ART. The CFIR construct of Evidence Strength and Quality was cited as an important factor in R-ART implementation. Buy-in from key stakeholders and immediate access to medications ensured the success of R-ART implementation. Patient acceptance of the condensed timeline for ART initiation was facilitated when presented in a patient-centered manner, including empathetic communication and addressing other patient needs concurrently. The condensed timeline of R-ART presented logistical challenges and opportunities for the development of intense patient-provider relationships. CONCLUSIONS: Results from the analysis showed that R-ART implementation should address the following: 1) logistical planning to implement HIV treatment with a condensed timeline 2) patients' mixed reactions to a new HIV diagnosis and 3) the high cost of HIV medications.","journal":"International Journal of STD & AIDS","year":2023,"id":367179,"datarank":0.29210943151840557,"base_score":1.791759469228055,"endowment":1.791759469228055,"self_citation_contribution":0.26876392038420827,"citation_network_contribution":0.02334551113419733,"self_endowment_contribution":0.26876392038420827,"citer_contribution":0.02334551113419733,"corpus_percentile":null,"corpus_rank":null,"citation_count":5,"citer_count":3,"citers_with_citation_signal":1,"citers_with_endowment":1,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9482,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":433887,"name":"Shawnika J. Hull","orcid":"0000-0002-3503-3289","position":1,"is_corresponding":false},{"id":760873,"name":"Aaron Broun","orcid":"0000-0001-6053-5478","position":2,"is_corresponding":false},{"id":1124807,"name":"Saanjh Boyani","orcid":null,"position":3,"is_corresponding":false},{"id":1124341,"name":"Darryl Moch","orcid":"0000-0002-9431-6553","position":4,"is_corresponding":false},{"id":1073983,"name":"Adam Visconti","orcid":"0000-0001-6257-1691","position":5,"is_corresponding":false},{"id":286384,"name":"Amanda D. Castel","orcid":"0000-0002-9095-2413","position":6,"is_corresponding":false},{"id":227356,"name":"Stefan Baral","orcid":"0000-0002-5482-2419","position":7,"is_corresponding":false},{"id":437628,"name":"Jonathan Colasanti","orcid":"0000-0002-0536-9769","position":8,"is_corresponding":false},{"id":426539,"name":"Allan Rodríguez","orcid":"0000-0001-9477-3327","position":9,"is_corresponding":false},{"id":815544,"name":"Joyce Jones","orcid":"0000-0001-5882-0907","position":10,"is_corresponding":false},{"id":462788,"name":"Susa Coffey","orcid":null,"position":11,"is_corresponding":false},{"id":444045,"name":"Anne K. Monroe","orcid":"0000-0003-3201-3845","position":12,"is_corresponding":false},{"id":981562,"name":"Rupali Doshi","orcid":"0000-0002-4799-7907","position":0,"is_corresponding":true}],"reference_count":30,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T01:15:12.215513Z","pmid":"37461333","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}