{"doi":"10.1177/095632020001100402","title":"Antiviral Therapy for Enteroviruses and Rhinoviruses","abstract":"<jats:p> The picornaviruses are a diverse group of viral pathogens that together comprise the most common causes of infection of humans in the developed world. Within the picornavirus family are three well-known groups of human pathogens — the rhinoviruses, the enteroviruses (including polioviruses, coxsackieviruses and echoviruses) and the hepatoviruses (including hepatitis A virus). This article will focus on the rhinoviruses and enteroviruses, agents for which substantial effort has been expended, and recent successes reported, toward the development of safe and effective antiviral therapy. </jats:p>","journal":"Antiviral Chemistry and Chemotherapy","year":2000,"id":24733,"datarank":3.1721153385145247,"base_score":4.07753744390572,"endowment":4.07753744390572,"self_citation_contribution":0.611630616585858,"citation_network_contribution":2.560484721928667,"self_endowment_contribution":0.611630616585858,"citer_contribution":2.560484721928667,"corpus_percentile":null,"corpus_rank":null,"citation_count":58,"citer_count":57,"citers_with_citation_signal":44,"citers_with_endowment":44,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":142085,"name":"Harley A Rotbart","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":4.07753744390572,"endowment":4.07753744390572,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"10950388","pmcid":null,"openalex_id":"https://openalex.org/W2066175267","authors":[],"funders":[],"total_grants":0,"fwci":3.3682,"citation_percentile":0.92852546,"influential_citations":3,"citation_trend":[{"year":2012,"count":2},{"year":2013,"count":2},{"year":2014,"count":1},{"year":2015,"count":2},{"year":2016,"count":2},{"year":2017,"count":3},{"year":2018,"count":2},{"year":2019,"count":1},{"year":2020,"count":1},{"year":2021,"count":4},{"year":2022,"count":3},{"year":2023,"count":2},{"year":2024,"count":2},{"year":2025,"count":1}],"oa_status":"bronze","license":"http://journals.sagepub.com/page/policies/text-and-data-mining-license","oa_locations":[{"url":"https://journals.sagepub.com/doi/pdf/10.1177/095632020001100402","host_type":"journal"},{"url":"https://journals.sagepub.com/doi/pdf/10.1177/095632020001100402","host_type":"BRONZE"},{"url":"https://journals.sagepub.com/doi/pdf/10.1177/095632020001100402","host_type":"publisher"},{"url":"https://doi.org/10.1177/095632020001100402","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/10950388","host_type":"repository"}],"fields_of_study":["Viral Infections and Immunology Research","Viral gastroenteritis research and epidemiology","Respiratory viral infections research","Biology","Medicine","Chemistry","3C Viral Proteases","Animals","Antiviral Agents","Benzimidazoles","Capsid","Cell Line","Common Cold","Cysteine Endopeptidases","Drug Resistance, Microbial","Enterovirus","Enterovirus Infections","Humans","Immunoglobulins, Intravenous","Interferons","Molecular Structure","Oximes","Picornaviridae Infections","Rhinovirus","Sulfonamides","Viral Proteins"],"mesh_terms":["3C Viral Proteases","Animals","Antiviral Agents","Benzimidazoles","Capsid","Cell Line","Common Cold","Cysteine Endopeptidases","Drug Resistance, Microbial","Enterovirus Infections","Enterovirus","Humans","Interferons","Oximes","Picornaviridae Infections","Rhinovirus","Sulfonamides","Viral Proteins","Molecular Structure","Immunoglobulins, Intravenous"],"keywords":["Coxsackievirus","Picornavirus","Echovirus","Rhinovirus","Virology","Picornaviridae","Enterovirus","Biology","Virus","Antiviral therapy","Ribavirin","Hepatitis C virus","Chronic hepatitis","RNA","Genetics"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-07T23:06:45.333828Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}