{"doi":"10.1177/03331024221132010","title":"The “index vein” as a sign for migraine aura in the emergency setting","abstract":"<jats:p>Background and objectives To assess the usefulness of the “index vein” for making the diagnosis of migraine aura.</jats:p>\n                  <jats:p>Methods 400 patients were included when they: i) presented with an acute neurological deficit, ii) had a brain MRI, and iii) had a discharge diagnosis of migraine aura, ischemic stroke, epileptic seizure or controls (n = 100 per group).</jats:p>\n                  <jats:p>Results Compared to stroke (2%), epileptic seizure (4%) and controls (1%), the index vein is more prevalent in migraine aura (17%, p &lt; 0.001). The index vein is highly specific for migraine aura (specificity 97%, 95% CI 95–99). The index vein has a positive predictive value for the diagnosis of migraine aura of 70% (95%CI 48–87). The index vein-score has the ability to diagnose migraine aura with a sensitivity of 94% (95%CI 87.4–97.8) and specificity of 73.5% (95%CI 66.8–79.5) at a cut-off of 4 points.</jats:p>\n                  <jats:p>Discussion The index vein serves as a good biomarker for migraine aura in the emergency setting.</jats:p>","journal":"Cephalalgia","year":2023,"id":14430,"datarank":0.350527660296344,"base_score":2.1972245773362196,"endowment":2.1972245773362196,"self_citation_contribution":0.32958368660043297,"citation_network_contribution":0.020943973695911066,"self_endowment_contribution":0.32958368660043297,"citer_contribution":0.020943973695911066,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":4,"citers_with_citation_signal":2,"citers_with_endowment":2,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":113997,"name":"Valentina Petroulia","orcid":null,"position":1,"is_corresponding":false},{"id":113998,"name":"Lara Schraml","orcid":null,"position":2,"is_corresponding":false},{"id":113999,"name":"Simon Jung","orcid":null,"position":3,"is_corresponding":false},{"id":114000,"name":"Mattia Branca","orcid":null,"position":4,"is_corresponding":false},{"id":114001,"name":"Morin Beyeler","orcid":"0000-0001-5911-7957","position":5,"is_corresponding":false},{"id":114002,"name":"Urs Fischer","orcid":null,"position":6,"is_corresponding":false},{"id":114003,"name":"Roland Wiest","orcid":null,"position":7,"is_corresponding":false},{"id":114004,"name":"Nedelina Slavova","orcid":null,"position":8,"is_corresponding":false},{"id":114005,"name":"Christoph J Schankin","orcid":"0000-0003-4668-6098","position":9,"is_corresponding":false},{"id":113996,"name":"Adrian Scutelnic","orcid":"0000-0001-9053-584X","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":2.1972245773362196,"endowment":2.1972245773362196,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"36622878","pmcid":null,"openalex_id":"https://openalex.org/W4313857297","authors":[],"funders":[],"total_grants":0,"fwci":1.6152,"citation_percentile":0.81885598,"influential_citations":0,"citation_trend":[{"year":2023,"count":3},{"year":2024,"count":2},{"year":2025,"count":3}],"oa_status":"hybrid","license":"cc-by-nc","oa_locations":[{"url":"https://journals.sagepub.com/doi/pdf/10.1177/03331024221132010","host_type":"journal"},{"url":"https://journals.sagepub.com/doi/pdf/10.1177/03331024221132010","host_type":"HYBRID"},{"url":"https://journals.sagepub.com/doi/pdf/10.1177/03331024221132010","host_type":"publisher"},{"url":"https://journals.sagepub.com/doi/full-xml/10.1177/03331024221132010","host_type":"publisher"},{"url":"https://doi.org/10.1177/03331024221132010","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/36622878","host_type":"repository"},{"url":"https://boris.unibe.ch/177113/","host_type":"repository"}],"fields_of_study":["Migraine and Headache Studies","Trigeminal Neuralgia and Treatments","Cardiovascular Syncope and Autonomic Disorders","Medicine","Humans","Migraine with Aura","Stroke","Epilepsy","Seizures","Magnetic Resonance Imaging"],"mesh_terms":["Epilepsy","Humans","Magnetic Resonance Imaging","Seizures","Migraine with Aura","Stroke"],"keywords":["Aura","Medicine","Migraine","Migraine with aura","Internal medicine","Stroke (engine)","Anesthesia","Cardiology","Epilepsy","Stroke","Migraine Aura","Index Vein"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-01T09:59:19.041610Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}