{"doi":"10.1177/000331978603700306","title":"Platelet Hyperaggregability, Blood Prostacyclin and Dipyridamole","abstract":"<jats:p>\n                    This study demonstrates the presence of PGI\n                    <jats:sub>2</jats:sub>\n                    in blood and its influence on platelet retention tests, possibly by the intermediate of a releasing system in the columns, which is followed by a proximate recuperation on the erythrocyte sites after the passage.\n                  </jats:p>\n                  <jats:p>The presence of prostacyclin on the erythrocyte sites seems to depend upon the red cell deformability in relation to the good condition of their erythrycote ATP reserve.</jats:p>\n                  <jats:p>The load of the erythrocyte sites increases with the daily dose of dipyrida mole. The maximum load of the sites appears to be reached with a daily dose of dipyridamole 450mg.</jats:p>\n                  <jats:p>Approximately 10% of the atherosclerosis patients who have been treated by dipyridamole keep their platelet hyperaggregability and their abnormally low ered prostacyclin level.</jats:p>","journal":"Angiology","year":1986,"id":34070,"datarank":0.2237093536478118,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"self_citation_contribution":0.16479184330021646,"citation_network_contribution":0.05891751034759535,"self_endowment_contribution":0.16479184330021646,"citer_contribution":0.05891751034759535,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":1,"citers_with_citation_signal":1,"citers_with_endowment":1,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":177097,"name":"M. Kahn","orcid":null,"position":1,"is_corresponding":false},{"id":177098,"name":"M. Cloarec","orcid":null,"position":2,"is_corresponding":false},{"id":177100,"name":"J. Van De Merckt","orcid":null,"position":3,"is_corresponding":false},{"id":177102,"name":"R. Sneppe","orcid":null,"position":4,"is_corresponding":false},{"id":177103,"name":"E. Schram","orcid":null,"position":5,"is_corresponding":false},{"id":177104,"name":"J.V. Fenollar","orcid":null,"position":6,"is_corresponding":false},{"id":177096,"name":"H. Solvay","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"3518548","pmcid":null,"openalex_id":"https://openalex.org/W1968537702","authors":[],"funders":[],"total_grants":0,"fwci":0.1954,"citation_percentile":0.44368891,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":"https://journals.sagepub.com/page/policies/text-and-data-mining-license","oa_locations":[{"url":"https://journals.sagepub.com/doi/pdf/10.1177/000331978603700306","host_type":"publisher"},{"url":"https://doi.org/10.1177/000331978603700306","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/3518548","host_type":"repository"},{"url":"http://hdl.handle.net/2078.1/54545","host_type":"repository"}],"fields_of_study":["Platelet Disorders and Treatments","Blood disorders and treatments","Antiplatelet Therapy and Cardiovascular Diseases","Medicine","6-Ketoprostaglandin F1 alpha","Adult","Aged","Arteriosclerosis","Binding Sites","Dipyridamole","Drug Administration Schedule","Epoprostenol","Erythrocytes","Female","Humans","Male","Middle Aged","Platelet Aggregation"],"mesh_terms":["Adult","Aged","Arteriosclerosis","Binding Sites","Dipyridamole","Drug Administration Schedule","Erythrocytes","Female","Humans","Male","Middle Aged","Platelet Aggregation","Epoprostenol","6-Ketoprostaglandin F1 alpha"],"keywords":["Dipyridamole","Prostacyclin","Platelet","Medicine","Internal medicine","Red blood cell","Cardiology","Red Cell","Endocrinology"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-09T17:34:31.779974Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}