{"doi":"10.1176/appi.ajp.2020.20020186","title":"Is Depression Nature or Nurture? Yes","abstract":null,"journal":"American Journal of Psychiatry","year":2020,"id":643318,"datarank":0.31191623125197543,"base_score":2.0794415416798357,"endowment":2.0794415416798357,"self_citation_contribution":0.31191623125197543,"citation_network_contribution":0.0,"self_endowment_contribution":0.31191623125197543,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":7,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":5360,"name":"Myrna M. Weissman","orcid":"0000-0003-3490-3075","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Is Depression Nature or Nurture? Yes","abstract":"I've increasingly felt that the correct answer to the question \"Is depression nature or nurture?\" is \"yes.\" In a landmark study in this issue, Kendler and colleagues (1) put substance to this answer. While the answer may still be \"yes,\" through the use of a cleverly designed natural experiment, Kendler et al. have identified a portion of nurture, the rearing environment, that can clearly be defined and even altered with intervention. In brief, they studied 666 high-risk full siblings, with high risk defined as having at least one parent with major depression, and 2,595 high-risk half siblings of which at least one was home-reared and one adopted away. What made this study possible were the large samples from a national registry in Sweden, the parental assessments, and the fact that in Sweden, where adoption is not common, adoptive families are selected to provide high-quality rearing environments, including high educational status, economic security, and a stable environment.","is_dataset_classified":null,"base_score":2.0794415416798357,"endowment":2.0794415416798357,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"32340465","pmcid":null,"openalex_id":"https://openalex.org/W3020020831","authors":[],"funders":[],"total_grants":0,"fwci":0.2546,"citation_percentile":0.67776684,"influential_citations":0,"citation_trend":[{"year":2020,"count":1},{"year":2021,"count":1},{"year":2023,"count":1},{"year":2024,"count":1},{"year":2025,"count":1},{"year":2026,"count":2}],"oa_status":"bronze","license":null,"oa_locations":[{"url":"https://ajp.psychiatryonline.org/doi/pdf/10.1176/appi.ajp.2020.20020186","host_type":"journal"},{"url":"https://ajp.psychiatryonline.org/doi/pdf/10.1176/appi.ajp.2020.20020186","host_type":"publisher"},{"url":"http://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2020.20020186","host_type":"publisher"},{"url":"https://doi.org/10.1176/appi.ajp.2020.20020186","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/32340465","host_type":"repository"}],"fields_of_study":["Child and Adolescent Psychosocial and Emotional Development","Cognitive Abilities and Testing","Child Welfare and Adoption"],"mesh_terms":["Depression","Major Depressive Disorder","Depressive Disorder, Major","Humans","Sweden","Siblings"],"keywords":["Nature versus nurture","Psychology","Depression (economics)","Social psychology","Developmental psychology","Sociology","Genetics","Genomics","Depressive Disorders","Environmental Risk Factors"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Quality Education"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-08T15:29:32.456521Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}