{"doi":"10.1172/jci145962","title":"It takes a village: lessons from collaborative science","abstract":"Like many physician-scientists, I started my research career in earnest during my fellowship training, which for me was an endocrinology fellowship in the 1990s. These were relatively early days in the era of using mouse genetics to elucidate in vivo biology and to model disease. The expectation was to obtain a K08 clinical investigator award and then leverage that work into an R01 grant. The traditional approach at that time was to focus on a scientific question that could be used to define your reputation in the field. In my case, my research centered on glucose transport (1, 2) and insulin signaling in the heart (3), largely based on insights gained from my prior work generating cardiomyocyte-restricted deletions of these metabolic regulators. I made the case that these murine models could inform the pathophysiology of diabetic cardiomyopathy, which at the time was beginning to be recognized as a distinct cardiovascular complication of diabetes. When I moved to the University of Utah in 2000 as an assistant professor, I presented a vision of developing a research program based on elucidating the contribution of changes in insulin signaling and glucose metabolism to diabetes-related heart failure and obtained individual grant funding from the NIH, the American Diabetes Association, and the American Heart Association to continue these studies as the sole principal investigator.","journal":"Journal of Clinical Investigation","year":2021,"id":211601,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9622,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":153753,"name":"E. Dale Abel","orcid":"0000-0001-5290-0738","position":0,"is_corresponding":true}],"reference_count":16,"raw_metadata":null,"created_at":"2026-07-18T23:52:20.112538Z","pmid":"33463544","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}