{"doi":"10.1167/iovs.66.3.40","title":"Age-Related Changes in Mesopic Reading Vision Across Adulthood","abstract":"Purpose: Reading is indispensable for daily activities such as reading books, menus, and food labels, occurring under a wide range of luminance conditions from mesopic (dim light) to photopic (daylight). Despite its significance, there has been limited attention on age-related changes in mesopic reading vision. The current study aims to investigate how mesopic reading vision changes across adulthood. Methods: Using the MNREAD iPad app, we assessed both mesopic (2 cd/m2) and photopic (220 cd/m2) reading vision in 157 normally-sighted individuals aged from 18 to 84, grouped into seven age groups. Reading vision was evaluated using four MNREAD parameters: maximum reading speed (MRS), critical print size (CPS), reading acuity (RA), and reading accessibility index (ACC). Results: There was a significant age-related decline in reading vision under both mesopic and photopic conditions, with a more pronounced decline observed in mesopic conditions. The decline was linear from age 20 to 80: MRS decreased by 30 words-per-minute in mesopic conditions and 29 words-per-minute in photopic conditions; ACC declined by 0.18 (mesopic) and 0.12 (photopic); CPS declined by 0.3 logMAR (mesopic) and 0.16 logMAR (photopic); RA declined by 0.24 logMAR (mesopic) and 0.18 logMAR (photopic). Conclusions: Our results show a monotonic decline in reading vision from ages 20 to 80 under both mesopic and photopic conditions, with a more pronounced decline in mesopic light. Given the significance of reading vision as a clinical measure, assessing reading vision under mesopic conditions may offer a more comprehensive evaluation of functional vision in everyday life.","journal":"Investigative Ophthalmology & Visual Science","year":2025,"id":519249,"datarank":0.29188652235829704,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"self_citation_contribution":0.29188652235829704,"citation_network_contribution":0.0,"self_endowment_contribution":0.29188652235829704,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":4,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9457,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1139564,"name":"Traci-Lin Goddin","orcid":null,"position":1,"is_corresponding":false},{"id":6866,"name":"David S. Friedman","orcid":"0000-0002-2055-5797","position":2,"is_corresponding":false},{"id":307656,"name":"Cynthia Owsley","orcid":"0000-0003-3424-011X","position":3,"is_corresponding":false},{"id":1011648,"name":"MiYoung Kwon","orcid":"0000-0002-0667-9494","position":4,"is_corresponding":false},{"id":1387590,"name":"Boris Peñaloza","orcid":"0000-0002-6988-5244","position":0,"is_corresponding":true}],"reference_count":87,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T02:49:18.751199Z","pmid":"40111357","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}