{"doi":"10.1162/imag_a_00020","title":"Test-retest reliability of the human connectome: An OPM-MEG study","abstract":"Abstract Magnetoencephalography with optically pumped magnetometers (OPM-MEG) offers a new way to record electrophysiological brain function, with significant advantages over conventional MEG, including adaptability to head shape/size, free movement during scanning, increased signal amplitude, and no reliance on cryogenics. However, OPM-MEG remains in its infancy, with significant questions to be answered regarding the optimal system design. Here, we present an open-source dataset acquired using a newly constructed OPM-MEG system with a triaxial sensor design, 168 channels, OPM-optimised magnetic shielding, and active background field control. We measure the test-retest reliability of the human connectome, which was computed using amplitude envelope correlation to measure whole-brain (parcellated) functional connectivity, in 10 individuals while they watch a 600 s move clip. Our results show high repeatability between experimental runs at the group level, with a correlation coefficient of 0.81 in the θ, 0.93 in α, and 0.94 in β frequency ranges. At the individual subject level, we found marked differences between individuals, but high within-subject robustness (correlations of 0.56 ± 0.25, 0.72 ± 0.15, and 0.78 ± 0.13 in α, θ, and β respectively). These results compare well to previous findings using conventional MEG and show that OPM-MEG is a viable way to robustly characterise connectivity.","journal":"Imaging Neuroscience","year":2023,"id":326660,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":28,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9614,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":336047,"name":"Sebastian Michelmann","orcid":"0000-0002-5717-586X","position":1,"is_corresponding":false},{"id":661896,"name":"Harrison Ritz","orcid":"0000-0003-3011-2946","position":2,"is_corresponding":false},{"id":806397,"name":"Vishal Shah","orcid":"0000-0003-0521-0034","position":3,"is_corresponding":false},{"id":806392,"name":"Ryan M. Hill","orcid":"0000-0002-1732-2095","position":4,"is_corresponding":false},{"id":807208,"name":"James Osborne","orcid":null,"position":5,"is_corresponding":false},{"id":844666,"name":"Cody Doyle","orcid":null,"position":6,"is_corresponding":false},{"id":806390,"name":"Niall Holmes","orcid":"0000-0002-0561-8366","position":7,"is_corresponding":false},{"id":315068,"name":"Richard Bowtell","orcid":"0000-0001-8656-412X","position":8,"is_corresponding":false},{"id":481139,"name":"Matthew J. Brookes","orcid":"0000-0002-8687-8185","position":9,"is_corresponding":false},{"id":269716,"name":"Kenneth A. Norman","orcid":"0000-0002-5887-9682","position":10,"is_corresponding":false},{"id":231578,"name":"Uri Hasson","orcid":"0000-0002-3599-7168","position":11,"is_corresponding":false},{"id":232162,"name":"Jonathan D. Cohen","orcid":"0000-0003-2316-0763","position":12,"is_corresponding":false},{"id":806393,"name":"Elena Boto","orcid":"0000-0002-0347-280X","position":13,"is_corresponding":false},{"id":849354,"name":"Lukas Rier","orcid":"0000-0002-4560-8787","position":0,"is_corresponding":true}],"reference_count":62,"raw_metadata":null,"created_at":"2026-07-19T01:08:37.840107Z","pmid":"40799699","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}