{"doi":"10.1161/jaha.118.010324","title":"Sex Differences in Receiving Layperson Cardiopulmonary Resuscitation in Pediatric Out‐of‐Hospital Cardiac Arrest: A Nationwide Cohort Study in Japan","abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background</jats:title>\n            <jats:p xml:lang=\"en\">\n              Layperson cardiopulmonary resuscitation (\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              ) is a crucial intervention for patients with out‐of‐hospital cardiac arrest (\n              <jats:styled-content style=\"fixed-case\">OHCA</jats:styled-content>\n              ). Although a sex disparity in receiving layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              (ie, female patients were less likely to receive layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              ) has been reported in adults, there are few data in the pediatric population, and we therefore investigated sex differences in receiving layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              in pediatric patients with\n              <jats:styled-content style=\"fixed-case\">OHCA</jats:styled-content>\n              .\n            </jats:p>\n          </jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results</jats:title>\n            <jats:p xml:lang=\"en\">\n              From the All‐Japan Utstein Registry, a prospective, nationwide, population‐based\n              <jats:styled-content style=\"fixed-case\">OHCA</jats:styled-content>\n              database, we included pediatric patients (≤17 years) with layperson‐witnessed\n              <jats:styled-content style=\"fixed-case\">OHCA</jats:styled-content>\n              from 2005 through 2015. The primary outcome was receiving layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              . Patient sex was the main exposure. We fitted multivariable logistic regression models to examine associations between patient sex and receiving layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              . We included a total of 4525 pediatric patients with layperson‐witnessed\n              <jats:styled-content style=\"fixed-case\">OHCA</jats:styled-content>\n              in this study, 1669 (36.9%) of whom were female. Female patients received layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              more often than male patients (831/1669 [49.8%] versus 1336/2856 [46.8%],\n              <jats:italic>P</jats:italic>\n              =0.05). After adjustment for age, time of day of arrest, year, witnesses persons, and dispatcher\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              instruction, the sex difference in receiving layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              was not significant (adjusted odds ratio for female subjects 1.14, 95% CI, 0.996‐1.31).\n            </jats:p>\n          </jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions</jats:title>\n            <jats:p xml:lang=\"en\">\n              In a pediatric population, female patients with layperson‐witnessed\n              <jats:styled-content style=\"fixed-case\">OHCA</jats:styled-content>\n              received layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              more often than male patients. After adjustment for covariates, there was no significant association between patient sex and receiving layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              .\n            </jats:p>\n          </jats:sec>","journal":"Journal of the American Heart Association","year":2019,"id":614684,"datarank":0.4493598410330987,"base_score":2.995732273553991,"endowment":2.995732273553991,"self_citation_contribution":0.4493598410330987,"citation_network_contribution":0.0,"self_endowment_contribution":0.4493598410330987,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":19,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1584006,"name":"Tasuku Matsuyama","orcid":null,"position":1,"is_corresponding":false},{"id":1584007,"name":"Koichiro Gibo","orcid":null,"position":2,"is_corresponding":false},{"id":642978,"name":"Sho Komukai","orcid":"0000-0002-4329-2520","position":3,"is_corresponding":false},{"id":642979,"name":"Junichi Izawa","orcid":"0000-0003-1920-8218","position":4,"is_corresponding":false},{"id":1584008,"name":"Kosuke Kiyohara","orcid":null,"position":5,"is_corresponding":false},{"id":1584010,"name":"Chika Nishiyama","orcid":null,"position":6,"is_corresponding":false},{"id":1584011,"name":"Takeyuki Kiguchi","orcid":null,"position":7,"is_corresponding":false},{"id":98909,"name":"Clifton W. Callaway","orcid":"0000-0002-3309-1573","position":8,"is_corresponding":false},{"id":1584014,"name":"Taku Iwami","orcid":null,"position":9,"is_corresponding":false},{"id":1584016,"name":"Tetsuhisa Kitamura","orcid":"0000-0003-0107-0580","position":10,"is_corresponding":false},{"id":332577,"name":"Masashi Okubo","orcid":"0000-0002-1447-8908","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Sex Differences in Receiving Layperson Cardiopulmonary Resuscitation in Pediatric Out‐of‐Hospital Cardiac Arrest: A Nationwide Cohort Study in Japan","abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background</jats:title>\n            <jats:p xml:lang=\"en\">\n              Layperson cardiopulmonary resuscitation (\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              ) is a crucial intervention for patients with out‐of‐hospital cardiac arrest (\n              <jats:styled-content style=\"fixed-case\">OHCA</jats:styled-content>\n              ). Although a sex disparity in receiving layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              (ie, female patients were less likely to receive layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              ) has been reported in adults, there are few data in the pediatric population, and we therefore investigated sex differences in receiving layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              in pediatric patients with\n              <jats:styled-content style=\"fixed-case\">OHCA</jats:styled-content>\n              .\n            </jats:p>\n          </jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results</jats:title>\n            <jats:p xml:lang=\"en\">\n              From the All‐Japan Utstein Registry, a prospective, nationwide, population‐based\n              <jats:styled-content style=\"fixed-case\">OHCA</jats:styled-content>\n              database, we included pediatric patients (≤17 years) with layperson‐witnessed\n              <jats:styled-content style=\"fixed-case\">OHCA</jats:styled-content>\n              from 2005 through 2015. The primary outcome was receiving layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              . Patient sex was the main exposure. We fitted multivariable logistic regression models to examine associations between patient sex and receiving layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              . We included a total of 4525 pediatric patients with layperson‐witnessed\n              <jats:styled-content style=\"fixed-case\">OHCA</jats:styled-content>\n              in this study, 1669 (36.9%) of whom were female. Female patients received layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              more often than male patients (831/1669 [49.8%] versus 1336/2856 [46.8%],\n              <jats:italic>P</jats:italic>\n              =0.05). After adjustment for age, time of day of arrest, year, witnesses persons, and dispatcher\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              instruction, the sex difference in receiving layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              was not significant (adjusted odds ratio for female subjects 1.14, 95% CI, 0.996‐1.31).\n            </jats:p>\n          </jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions</jats:title>\n            <jats:p xml:lang=\"en\">\n              In a pediatric population, female patients with layperson‐witnessed\n              <jats:styled-content style=\"fixed-case\">OHCA</jats:styled-content>\n              received layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              more often than male patients. After adjustment for covariates, there was no significant association between patient sex and receiving layperson\n              <jats:styled-content style=\"fixed-case\">CPR</jats:styled-content>\n              .\n            </jats:p>\n          </jats:sec>","is_dataset_classified":null,"base_score":2.995732273553991,"endowment":2.995732273553991,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"30587069","pmcid":"PMC6405730","openalex_id":"https://openalex.org/W2905726621","authors":[],"funders":[],"total_grants":0,"fwci":1.6364,"citation_percentile":0.84607673,"influential_citations":0,"citation_trend":[{"year":2019,"count":1},{"year":2020,"count":3},{"year":2021,"count":2},{"year":2022,"count":3},{"year":2023,"count":1},{"year":2024,"count":3},{"year":2025,"count":5},{"year":2026,"count":1}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://doi.org/10.1161/jaha.118.010324","host_type":"journal"},{"url":"https://doi.org/10.1161/jaha.118.010324","host_type":"publisher"},{"url":"https://www.ahajournals.org/doi/full/10.1161/JAHA.118.010324","host_type":"publisher"},{"url":"https://pubmed.ncbi.nlm.nih.gov/30587069","host_type":"repository"},{"url":"http://hdl.handle.net/2433/236022","host_type":"repository"},{"url":"https://hdl.handle.net/11094/78388","host_type":"repository"},{"url":"https://doaj.org/article/8669def67fb040d787f08df648d7057f","host_type":"repository"},{"url":"http://europepmc.org/pmc/articles/PMC6405730","host_type":"repository"},{"url":"https://doi.org/10.1161/JAHA.118.010324","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6405730","host_type":"repository"},{"url":"https://ir.library.osaka-u.ac.jp/repo/ouka/all/78388/JAmHeartAssoc_08_010324.pdf","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC6405730","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC6405730?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Cardiac Arrest and Resuscitation","Injury Epidemiology and Prevention","Mechanical Circulatory Support Devices","Adolescent","Cardiopulmonary Resuscitation","Child","Child, Preschool","Emergency Medical Services","Female","Follow-Up Studies","Humans","Infant","Infant, Newborn","Japan","Male","Out-of-Hospital Cardiac Arrest","Population Surveillance","Prospective Studies","Registries","Sex Distribution","Sex Factors","Survival Rate","Time Factors"],"mesh_terms":["Adolescent","Child","Child, Preschool","Emergency Medical Services","Female","Follow-Up Studies","Humans","Infant","Infant, Newborn","Japan","Male","Population Surveillance","Prospective Studies","Registries","Sex Factors","Time Factors","Survival Rate","Cardiopulmonary Resuscitation","Sex Distribution","Out-of-Hospital Cardiac Arrest"],"keywords":["Layperson","Medicine","Cardiopulmonary resuscitation","Population","Emergency medicine","Resuscitation","Pediatrics","Pediatric","Cardiac arrest","Gender Differences"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-02T15:22:03.175903Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}