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Fibrin network properties, including fibre thickness, branchpoint density, fibre density, mechanical stability, porosity, and resistance to lysis can differentiate plasma clots of healthy individuals from those with haemostatic or thrombotic disorders. Plasma from patients with a bleeding history produces thick, minimally-branched fibres in coarse, deformable networks that are highly susceptible to lysis, whereas plasma from patients with a personal or family history of thrombosis produces thin, highly-branched fibres in impermeable, rigid networks that are relatively resistant to fibrinolysis (1).","is_dataset_classified":null,"base_score":4.499809670330265,"endowment":4.499809670330265,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"20886193","pmcid":"PMC3236083","openalex_id":"https://openalex.org/W2111904298","authors":[],"funders":[{"funder_name":"NHLBI NIH HHS","grant_id":"R01 HL094740","title":null},{"funder_name":"NIBIB NIH HHS","grant_id":"P41EB002025","title":null},{"funder_name":"NIEHS NIH HHS","grant_id":"T32 ES007017","title":null}],"total_grants":3,"fwci":4.1954,"citation_percentile":0.94307582,"influential_citations":0,"citation_trend":[{"year":2012,"count":5},{"year":2013,"count":9},{"year":2014,"count":5},{"year":2015,"count":7},{"year":2016,"count":9},{"year":2017,"count":8},{"year":2018,"count":4},{"year":2019,"count":7},{"year":2020,"count":5},{"year":2021,"count":4},{"year":2022,"count":5},{"year":2023,"count":3},{"year":2024,"count":4},{"year":2025,"count":3},{"year":2026,"count":5}],"oa_status":"bronze","license":null,"oa_locations":[{"url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1160/TH10-07-0442.pdf","host_type":"journal"},{"url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1160/TH10-07-0442.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1160/th10-07-0442","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/20886193","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3236083","host_type":"repository"}],"fields_of_study":["Blood properties and coagulation","Platelet Disorders and Treatments","Blood Coagulation and Thrombosis Mechanisms"],"mesh_terms":["Blood Coagulation","Cells, Cultured","Fibrin","Hemostasis","Humans","Protein Conformation","Regional Blood Flow","Stress, Mechanical","Thromboplastin"],"keywords":["Fibrin","Clot formation","Flow (mathematics)","Fibrinogen","Thrombosis","Hemostasis","Chemistry","Medicine","Surgery","Immunology","Internal medicine","Mechanics"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-10T03:22:22.475138Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}