{"doi":"10.1155/2022/1338214","title":"Influences of Antithrombotic Elastic Socks Combined with Air Pressure in Reducing Lower Extremity Deep Venous Thrombosis for Patients Undergoing Cardiothoracic Surgery","abstract":"<jats:p>\n                    This study was designed to investigate the application and therapeutic effect of antithrombotic elastic socks combined with air pressure in the prevention of lower extremity deep venous thrombosis in patients undergoing cardiothoracic surgery. Sixty patients in cardiothoracic surgery of our hospital from January 2019 to December 2020 were randomly divided into a study group and control group. The control group was treated with routine treatment intervention. Based on routine treatment intervention, the study group was treated with antithrombotic elastic socks combined with pneumatic treatment intervention. The activated partial thromboplastin time (APTT), thrombin time (TT), femoral venous blood flow velocity of both lower limbs, and the incidence of lower extremity deep venous thrombosis (LEDVT), postoperative lower extremity swelling, inflammatory factors, and satisfaction were measured. After intervention, APTT (\n                    <jats:inline-formula>\n                      <a:math xmlns:a=\"http://www.w3.org/1998/Math/MathML\" id=\"M1\">\n                        <a:mn>31.74</a:mn>\n                        <a:mo>±</a:mo>\n                        <a:mn>1.15</a:mn>\n                      </a:math>\n                    </jats:inline-formula>\n                     s) and TT (\n                    <jats:inline-formula>\n                      <c:math xmlns:c=\"http://www.w3.org/1998/Math/MathML\" id=\"M2\">\n                        <c:mn>14.58</c:mn>\n                        <c:mo>±</c:mo>\n                        <c:mn>0.24</c:mn>\n                      </c:math>\n                    </jats:inline-formula>\n                     s) in the study group were higher than those in the control group APTT (\n                    <jats:inline-formula>\n                      <e:math xmlns:e=\"http://www.w3.org/1998/Math/MathML\" id=\"M3\">\n                        <e:mn>25.13</e:mn>\n                        <e:mo>±</e:mo>\n                        <e:mn>1.14</e:mn>\n                      </e:math>\n                    </jats:inline-formula>\n                     s) and TT (\n                    <jats:inline-formula>\n                      <g:math xmlns:g=\"http://www.w3.org/1998/Math/MathML\" id=\"M4\">\n                        <g:mn>12.14</g:mn>\n                        <g:mo>±</g:mo>\n                        <g:mn>0.23</g:mn>\n                      </g:math>\n                    </jats:inline-formula>\n                     s) (\n                    <jats:inline-formula>\n                      <i:math xmlns:i=\"http://www.w3.org/1998/Math/MathML\" id=\"M5\">\n                        <i:mi>P</i:mi>\n                        <i:mo>&lt;</i:mo>\n                        <i:mn>0.05</i:mn>\n                      </i:math>\n                    </jats:inline-formula>\n                    ). The left lower limb femoral vein blood flow velocity and the right lower limb femoral vein blood flow velocity in the study group were better than those in the control group (\n                    <jats:inline-formula>\n                      <k:math xmlns:k=\"http://www.w3.org/1998/Math/MathML\" id=\"M6\">\n                        <k:mi>P</k:mi>\n                        <k:mo>&lt;</k:mo>\n                        <k:mn>0.05</k:mn>\n                      </k:math>\n                    </jats:inline-formula>\n                    ). The incidence of postoperative lower limb swelling and deep vein in the study group was lower than that in the control group (\n                    <jats:inline-formula>\n                      <m:math xmlns:m=\"http://www.w3.org/1998/Math/MathML\" id=\"M7\">\n                        <m:mi>P</m:mi>\n                        <m:mo>&lt;</m:mo>\n                        <m:mn>0.05</m:mn>\n                      </m:math>\n                    </jats:inline-formula>\n                    ). Serum tumor necrosis factor alpha and interleukin-6 concentrations in the study group were lower than those in the control group (\n                    <jats:inline-formula>\n                      <o:math xmlns:o=\"http://www.w3.org/1998/Math/MathML\" id=\"M8\">\n                        <o:mi>P</o:mi>\n                        <o:mo>&lt;</o:mo>\n                        <o:mn>0.05</o:mn>\n                      </o:math>\n                    </jats:inline-formula>\n                    ). The satisfaction rate of patients in the study group (93.33%) was significantly higher than that in the control group (70.00%) (\n                    <jats:inline-formula>\n                      <q:math xmlns:q=\"http://www.w3.org/1998/Math/MathML\" id=\"M9\">\n                        <q:mi>P</q:mi>\n                        <q:mo>&lt;</q:mo>\n                        <q:mn>0.05</q:mn>\n                      </q:math>\n                    </jats:inline-formula>\n                    ). In conclusion, after cardiothoracic surgery, antithrombotic elastic socks combined with air pressure can significantly reduce the incidence of LEDVT by improving patients’ coagulation function, reducing inflammatory reaction. It is worthy of popularization and application in relevant surgery.\n                  </jats:p>","journal":"Computational and Mathematical Methods in Medicine","year":2022,"id":658730,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1367136,"name":"Qun Zhang","orcid":"0000-0002-2773-3437","position":1,"is_corresponding":false},{"id":1013658,"name":"Xuemei Sun","orcid":"0000-0002-2583-8593","position":2,"is_corresponding":false},{"id":1349522,"name":"Yan Gu","orcid":"0000-0002-0193-2606","position":3,"is_corresponding":false},{"id":1719605,"name":"Weihong Fu","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Influences of Antithrombotic Elastic Socks Combined with Air Pressure in Reducing Lower Extremity Deep Venous Thrombosis for Patients Undergoing Cardiothoracic Surgery","abstract":"<jats:p>\n                    This study was designed to investigate the application and therapeutic effect of antithrombotic elastic socks combined with air pressure in the prevention of lower extremity deep venous thrombosis in patients undergoing cardiothoracic surgery. Sixty patients in cardiothoracic surgery of our hospital from January 2019 to December 2020 were randomly divided into a study group and control group. The control group was treated with routine treatment intervention. Based on routine treatment intervention, the study group was treated with antithrombotic elastic socks combined with pneumatic treatment intervention. The activated partial thromboplastin time (APTT), thrombin time (TT), femoral venous blood flow velocity of both lower limbs, and the incidence of lower extremity deep venous thrombosis (LEDVT), postoperative lower extremity swelling, inflammatory factors, and satisfaction were measured. After intervention, APTT (\n                    <jats:inline-formula>\n                      <a:math xmlns:a=\"http://www.w3.org/1998/Math/MathML\" id=\"M1\">\n                        <a:mn>31.74</a:mn>\n                        <a:mo>±</a:mo>\n                        <a:mn>1.15</a:mn>\n                      </a:math>\n                    </jats:inline-formula>\n                     s) and TT (\n                    <jats:inline-formula>\n                      <c:math xmlns:c=\"http://www.w3.org/1998/Math/MathML\" id=\"M2\">\n                        <c:mn>14.58</c:mn>\n                        <c:mo>±</c:mo>\n                        <c:mn>0.24</c:mn>\n                      </c:math>\n                    </jats:inline-formula>\n                     s) in the study group were higher than those in the control group APTT (\n                    <jats:inline-formula>\n                      <e:math xmlns:e=\"http://www.w3.org/1998/Math/MathML\" id=\"M3\">\n                        <e:mn>25.13</e:mn>\n                        <e:mo>±</e:mo>\n                        <e:mn>1.14</e:mn>\n                      </e:math>\n                    </jats:inline-formula>\n                     s) and TT (\n                    <jats:inline-formula>\n                      <g:math xmlns:g=\"http://www.w3.org/1998/Math/MathML\" id=\"M4\">\n                        <g:mn>12.14</g:mn>\n                        <g:mo>±</g:mo>\n                        <g:mn>0.23</g:mn>\n                      </g:math>\n                    </jats:inline-formula>\n                     s) (\n                    <jats:inline-formula>\n                      <i:math xmlns:i=\"http://www.w3.org/1998/Math/MathML\" id=\"M5\">\n                        <i:mi>P</i:mi>\n                        <i:mo>&lt;</i:mo>\n                        <i:mn>0.05</i:mn>\n                      </i:math>\n                    </jats:inline-formula>\n                    ). The left lower limb femoral vein blood flow velocity and the right lower limb femoral vein blood flow velocity in the study group were better than those in the control group (\n                    <jats:inline-formula>\n                      <k:math xmlns:k=\"http://www.w3.org/1998/Math/MathML\" id=\"M6\">\n                        <k:mi>P</k:mi>\n                        <k:mo>&lt;</k:mo>\n                        <k:mn>0.05</k:mn>\n                      </k:math>\n                    </jats:inline-formula>\n                    ). The incidence of postoperative lower limb swelling and deep vein in the study group was lower than that in the control group (\n                    <jats:inline-formula>\n                      <m:math xmlns:m=\"http://www.w3.org/1998/Math/MathML\" id=\"M7\">\n                        <m:mi>P</m:mi>\n                        <m:mo>&lt;</m:mo>\n                        <m:mn>0.05</m:mn>\n                      </m:math>\n                    </jats:inline-formula>\n                    ). Serum tumor necrosis factor alpha and interleukin-6 concentrations in the study group were lower than those in the control group (\n                    <jats:inline-formula>\n                      <o:math xmlns:o=\"http://www.w3.org/1998/Math/MathML\" id=\"M8\">\n                        <o:mi>P</o:mi>\n                        <o:mo>&lt;</o:mo>\n                        <o:mn>0.05</o:mn>\n                      </o:math>\n                    </jats:inline-formula>\n                    ). The satisfaction rate of patients in the study group (93.33%) was significantly higher than that in the control group (70.00%) (\n                    <jats:inline-formula>\n                      <q:math xmlns:q=\"http://www.w3.org/1998/Math/MathML\" id=\"M9\">\n                        <q:mi>P</q:mi>\n                        <q:mo>&lt;</q:mo>\n                        <q:mn>0.05</q:mn>\n                      </q:math>\n                    </jats:inline-formula>\n                    ). In conclusion, after cardiothoracic surgery, antithrombotic elastic socks combined with air pressure can significantly reduce the incidence of LEDVT by improving patients’ coagulation function, reducing inflammatory reaction. It is worthy of popularization and application in relevant surgery.\n                  </jats:p>","is_dataset_classified":null,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"36105248","pmcid":"PMC9467765","openalex_id":"https://openalex.org/W4294663763","authors":[],"funders":[],"total_grants":0,"fwci":0.2067,"citation_percentile":0.52793879,"influential_citations":0,"citation_trend":[{"year":2023,"count":1}],"oa_status":"hybrid","license":"cc-by","oa_locations":[{"url":"https://downloads.hindawi.com/journals/cmmm/2022/1338214.pdf","host_type":"journal"},{"url":"https://downloads.hindawi.com/journals/cmmm/2022/1338214.pdf","host_type":"publisher"},{"url":"http://downloads.hindawi.com/journals/cmmm/2022/1338214.pdf","host_type":"publisher"},{"url":"http://downloads.hindawi.com/journals/cmmm/2022/1338214.xml","host_type":"publisher"},{"url":"https://doi.org/10.1155/2022/1338214","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/36105248","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9467765","host_type":"repository"},{"url":"https://doaj.org/article/87ac119ab27b4fc2b55a5b6bfe78a31b","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC9467765","host_type":"Europe_PMC"}],"fields_of_study":["Venous Thromboembolism Diagnosis and Management","Diagnosis and Treatment of Venous Diseases","Vascular Procedures and Complications","Air Pressure","Fibrinolytic Agents","Humans","Leg","Lower Extremity","Venous Thrombosis"],"mesh_terms":["Air Pressure","Fibrinolytic Agents","Humans","Leg","Venous Thrombosis","Lower Extremity"],"keywords":["Antithrombotic","Thrombosis","Medicine","Venous thrombosis","Partial thromboplastin time","Surgery","Internal medicine","Coagulation"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-12T05:11:09.358816Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}