{"doi":"10.1155/2021/5599023","title":"The Effectiveness of Cancer Pain Management in a Tertiary Hospital Outpatient Pain Clinic in Thailand: A Prospective Observational Study","abstract":"<jats:p>Context. In a previous retrospective study, cancer pain management was effective in 47.5% of a cohort assessed after 3 months in a pain clinic at Siriraj Hospital. New guidelines were established, including a multidisciplinary approach, availability of pain interventions, and palliative care referral. Objectives. The objective was to examine the effectiveness of the updated approach. Methods. With IRB approval, outpatients with cancer were enrolled from January to December 2018. Assessments were recorded at baseline and three consecutive visits (BL, FU1, FU2, and FU3), including Numerical Rating Scale (NRS), the Brief Pain Inventory (BPI), the Edmonton Symptom Assessment System (ESAS), side effects, and analgesic use. The primary outcome was a favorable response, defined as an NRS decrease more than 30% or NRS &lt;4. Secondary outcomes included trends over time in BPI, ESAS, side effects, and analgesic use. Pain response predictors at FU3 were analyzed using logistic regression. Results. Among 150 patients, 72 (48%) completed follow-ups. Of these, 61% achieved a favorable response at FU3. Pain interference diminished at all visits relative to baseline (<jats:inline-formula>\n                     <a:math xmlns:a=\"http://www.w3.org/1998/Math/MathML\" id=\"M1\">\n                        <a:mi>p</a:mi>\n                        <a:mo>&lt;</a:mo>\n                        <a:mn>0.05</a:mn>\n                     </a:math>\n                  </jats:inline-formula>). Median morphine equivalent daily dosage (MEDD) at BL was 20 mg/day, with a statistically significant, but clinically modest increase to 26.4 mg/day at FU3. Radiation therapy during pain care was a predictor of pain responders. Conclusion. The current Siriraj multidisciplinary approach provided effective relief of pain and stabilization of other cancer-related symptoms. Radiation therapy during pain care can be used to predict pain outcomes. Ongoing improvement domains were identified and considered in the context of cultural, economic, and geographic factors.</jats:p>","journal":"Pain Research and Management","year":2021,"id":624214,"datarank":0.24141568686511508,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"self_citation_contribution":0.24141568686511508,"citation_network_contribution":0.0,"self_endowment_contribution":0.24141568686511508,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1613510,"name":"Skaorat Panchoowong","orcid":"0000-0002-8152-7343","position":1,"is_corresponding":false},{"id":1016664,"name":"Carolina Donado","orcid":"0000-0003-4345-9201","position":2,"is_corresponding":false},{"id":1613512,"name":"Kimberly Lobo","orcid":"0000-0003-4328-4894","position":3,"is_corresponding":false},{"id":1613513,"name":"Pimporn Phankhongsap","orcid":"0000-0002-1619-9013","position":4,"is_corresponding":false},{"id":1613515,"name":"Pinyo Sriveerachai","orcid":"0000-0002-8874-3030","position":5,"is_corresponding":false},{"id":1081713,"name":"Pramote Euasobhon","orcid":"0000-0001-5268-5476","position":6,"is_corresponding":false},{"id":1613517,"name":"Pranee Rushatamukayanunt","orcid":"0000-0003-3596-3598","position":7,"is_corresponding":false},{"id":1613518,"name":"Sahatsa Mandee","orcid":"0000-0003-2232-0315","position":8,"is_corresponding":false},{"id":710210,"name":"Nantthasorn Zinboonyahgoon","orcid":"0000-0002-5946-7962","position":9,"is_corresponding":false},{"id":776376,"name":"Charles B. Berde","orcid":"0000-0002-1801-6399","position":10,"is_corresponding":false},{"id":1613508,"name":"Suratsawadee Wangnamthip","orcid":"0000-0002-6795-8550","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"The Effectiveness of Cancer Pain Management in a Tertiary Hospital Outpatient Pain Clinic in Thailand: A Prospective Observational Study","abstract":"<jats:p>Context. In a previous retrospective study, cancer pain management was effective in 47.5% of a cohort assessed after 3 months in a pain clinic at Siriraj Hospital. New guidelines were established, including a multidisciplinary approach, availability of pain interventions, and palliative care referral. Objectives. The objective was to examine the effectiveness of the updated approach. Methods. With IRB approval, outpatients with cancer were enrolled from January to December 2018. Assessments were recorded at baseline and three consecutive visits (BL, FU1, FU2, and FU3), including Numerical Rating Scale (NRS), the Brief Pain Inventory (BPI), the Edmonton Symptom Assessment System (ESAS), side effects, and analgesic use. The primary outcome was a favorable response, defined as an NRS decrease more than 30% or NRS &lt;4. Secondary outcomes included trends over time in BPI, ESAS, side effects, and analgesic use. Pain response predictors at FU3 were analyzed using logistic regression. Results. Among 150 patients, 72 (48%) completed follow-ups. Of these, 61% achieved a favorable response at FU3. Pain interference diminished at all visits relative to baseline (<jats:inline-formula>\n                     <a:math xmlns:a=\"http://www.w3.org/1998/Math/MathML\" id=\"M1\">\n                        <a:mi>p</a:mi>\n                        <a:mo>&lt;</a:mo>\n                        <a:mn>0.05</a:mn>\n                     </a:math>\n                  </jats:inline-formula>). Median morphine equivalent daily dosage (MEDD) at BL was 20 mg/day, with a statistically significant, but clinically modest increase to 26.4 mg/day at FU3. Radiation therapy during pain care was a predictor of pain responders. Conclusion. The current Siriraj multidisciplinary approach provided effective relief of pain and stabilization of other cancer-related symptoms. Radiation therapy during pain care can be used to predict pain outcomes. Ongoing improvement domains were identified and considered in the context of cultural, economic, and geographic factors.</jats:p>","is_dataset_classified":null,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"34336068","pmcid":"PMC8315883","openalex_id":"https://openalex.org/W3186181614","authors":[],"funders":[{"funder_name":"Faculty of Medicine Siriraj Hospital, Mahidol University","grant_id":"R016135008","title":null}],"total_grants":1,"fwci":0.9455,"citation_percentile":0.75112911,"influential_citations":0,"citation_trend":[{"year":2023,"count":1},{"year":2024,"count":3}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://downloads.hindawi.com/journals/prm/2021/5599023.pdf","host_type":"journal"},{"url":"https://downloads.hindawi.com/journals/prm/2021/5599023.pdf","host_type":"publisher"},{"url":"http://downloads.hindawi.com/journals/prm/2021/5599023.pdf","host_type":"publisher"},{"url":"http://downloads.hindawi.com/journals/prm/2021/5599023.xml","host_type":"publisher"},{"url":"https://doi.org/10.1155/2021/5599023","host_type":"journal"},{"url":"https://dialnet.unirioja.es/servlet/articulo?codigo=1078777","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/34336068","host_type":"repository"},{"url":"https://doaj.org/article/98b4ba48058247d4bb35a7da553e8ff1","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8315883","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC8315883","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC8315883?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Pain Management and Opioid Use","Palliative Care and End-of-Life Issues","Oral health in cancer treatment"],"mesh_terms":["Cancer Pain","Aged","Female","Humans","Male","Middle Aged","Neoplasms","Outpatients","Prospective Studies","Thailand","Pain Clinics","Pain Management","Tertiary Care Centers"],"keywords":["Medicine","Cancer pain","Brief Pain Inventory","Palliative care","Context (archaeology)","Referral","Physical therapy","Analgesic","Observational study","Psychological intervention","Pain assessment","Cancer","Internal medicine","Chronic pain","Pain management","Family medicine","Anesthesia","Psychiatry"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"nct"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-04T03:04:56.549853Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}