{"doi":"10.1155/2019/8591631","title":"Effects of Fe<sup>3+</sup> on Acute Toxicity and Regeneration of Planarian (<i>Dugesia japonica</i>) at Different Temperatures","abstract":"<jats:p><jats:italic>Objective</jats:italic>. To investigate the effects of different concentrations of Fe<jats:sup>3+</jats:sup> on the acute toxicity and regeneration of planarian at different temperatures.<jats:italic> Method</jats:italic>. The planarians were treated with 40 mg/l, 50 mg/l, 60 mg/l, and 70 mg/l Fe<jats:sup>3+</jats:sup> solution and placed in 15°C, 20°C, and 25°C, respectively, to observe the mortality and the poisoning pattern of the planarian. In addition, the planarians were cut into three parts of head, trunk, and tail, then placed in Fe<jats:sup>3+</jats:sup> solution at concentrations of 10 mg/l, 15 mg/l, 20 mg/l, and 30 mg/l, and placed in 15°C, 20°C, and 25°C respectively, and the regeneration rate of the planarian was investigated.<jats:italic> Results</jats:italic>. At the same temperature, in the concentration of Fe<jats:sup>3+</jats:sup> from 40 mg/l to 70 mg/l, the mortality of the planarian increased with the increasing of the concentration of Fe<jats:sup>3+</jats:sup>; at the same concentration and different temperatures, the death speed of the planarian is the fastest at 20°C, the next at 25°C, and the lowest at 15°C, indicating that the toxic effect of Fe<jats:sup>3+</jats:sup> can be accelerated at a suitable temperature of 20°C. At the same temperature, in the low concentration of Fe<jats:sup>3+</jats:sup> from 10 mg/l to 30 mg/l, the regeneration rate of the planarian gradually decreased with the increasing of the concentration of Fe<jats:sup>3+</jats:sup>; at the same concentration and different temperature, the regeneration rate of planarian was faster at 20°C and 25°C, but the difference between 20°C and 25°C was small, and the slowest at 15°C, indicating that the low temperature significantly affects the planarian regeneration speed. The study also found the regeneration rates of the head, trunk, and tail of the planarian were different; the head regeneration was the fastest, the trunk was the second, and the tail was the slowest.<jats:italic> Conclusion</jats:italic>. Fe<jats:sup>3+</jats:sup> had obvious toxic effects on the survival and regeneration of planarian; the planarian is sensitive to Fe<jats:sup>3+</jats:sup> and may be used to detect Fe<jats:sup>3+</jats:sup> water pollution; in addition, temperature can affect the toxic effects of Fe<jats:sup>3+</jats:sup> and thus affect the survival and regeneration of the planarian. Therefore, the temperature should be taken into consideration when detecting water Fe<jats:sup>3+</jats:sup> pollution.</jats:p>","journal":"BioMed Research International","year":2019,"id":660491,"datarank":0.515098080672772,"base_score":3.4339872044851463,"endowment":3.4339872044851463,"self_citation_contribution":0.515098080672772,"citation_network_contribution":0.0,"self_endowment_contribution":0.515098080672772,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":30,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1724217,"name":"Linxia Song","orcid":null,"position":1,"is_corresponding":false},{"id":1724220,"name":"Yahong Han","orcid":null,"position":2,"is_corresponding":false},{"id":935823,"name":"Yingbo Wang","orcid":"0000-0002-8835-3681","position":3,"is_corresponding":false},{"id":1724227,"name":"Xiaowang Tang","orcid":null,"position":4,"is_corresponding":false},{"id":1724232,"name":"Guicai Cui","orcid":null,"position":5,"is_corresponding":false},{"id":1724235,"name":"Zhenbiao Xu","orcid":"0000-0001-8102-3009","position":6,"is_corresponding":false},{"id":1287434,"name":"Xue Ding","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Effects of Fe<sup>3+</sup> on Acute Toxicity and Regeneration of Planarian (<i>Dugesia japonica</i>) at Different Temperatures","abstract":"<jats:p><jats:italic>Objective</jats:italic>. To investigate the effects of different concentrations of Fe<jats:sup>3+</jats:sup> on the acute toxicity and regeneration of planarian at different temperatures.<jats:italic> Method</jats:italic>. The planarians were treated with 40 mg/l, 50 mg/l, 60 mg/l, and 70 mg/l Fe<jats:sup>3+</jats:sup> solution and placed in 15°C, 20°C, and 25°C, respectively, to observe the mortality and the poisoning pattern of the planarian. In addition, the planarians were cut into three parts of head, trunk, and tail, then placed in Fe<jats:sup>3+</jats:sup> solution at concentrations of 10 mg/l, 15 mg/l, 20 mg/l, and 30 mg/l, and placed in 15°C, 20°C, and 25°C respectively, and the regeneration rate of the planarian was investigated.<jats:italic> Results</jats:italic>. At the same temperature, in the concentration of Fe<jats:sup>3+</jats:sup> from 40 mg/l to 70 mg/l, the mortality of the planarian increased with the increasing of the concentration of Fe<jats:sup>3+</jats:sup>; at the same concentration and different temperatures, the death speed of the planarian is the fastest at 20°C, the next at 25°C, and the lowest at 15°C, indicating that the toxic effect of Fe<jats:sup>3+</jats:sup> can be accelerated at a suitable temperature of 20°C. At the same temperature, in the low concentration of Fe<jats:sup>3+</jats:sup> from 10 mg/l to 30 mg/l, the regeneration rate of the planarian gradually decreased with the increasing of the concentration of Fe<jats:sup>3+</jats:sup>; at the same concentration and different temperature, the regeneration rate of planarian was faster at 20°C and 25°C, but the difference between 20°C and 25°C was small, and the slowest at 15°C, indicating that the low temperature significantly affects the planarian regeneration speed. The study also found the regeneration rates of the head, trunk, and tail of the planarian were different; the head regeneration was the fastest, the trunk was the second, and the tail was the slowest.<jats:italic> Conclusion</jats:italic>. Fe<jats:sup>3+</jats:sup> had obvious toxic effects on the survival and regeneration of planarian; the planarian is sensitive to Fe<jats:sup>3+</jats:sup> and may be used to detect Fe<jats:sup>3+</jats:sup> water pollution; in addition, temperature can affect the toxic effects of Fe<jats:sup>3+</jats:sup> and thus affect the survival and regeneration of the planarian. Therefore, the temperature should be taken into consideration when detecting water Fe<jats:sup>3+</jats:sup> pollution.</jats:p>","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"31534964","pmcid":"PMC6724543","openalex_id":null,"authors":[],"funders":[{"funder_name":"National Natural Science Foundation of China","grant_id":"31550005","title":null},{"funder_name":"National Natural Science Foundation of China","grant_id":"31350004","title":null}],"total_grants":2,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":null,"license":"http://creativecommons.org/licenses/by/4.0/","oa_locations":[{"url":"http://downloads.hindawi.com/journals/bmri/2019/8591631.pdf","host_type":"publisher"},{"url":"http://downloads.hindawi.com/journals/bmri/2019/8591631.xml","host_type":"publisher"},{"url":"https://downloads.hindawi.com/journals/bmri/2019/8591631.pdf","host_type":"Unpaywall"},{"url":"https://europepmc.org/articles/PMC6724543","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC6724543?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":[],"mesh_terms":["Animals","Planarians","Iron","Ferric Compounds","Regeneration","Time Factors","Hot Temperature"],"keywords":[],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-12T09:18:48.270928Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}