{"doi":"10.1155/2017/7425925","title":"Frequency and Predictors of Self-Reported Hypoglycemia in Insulin-Treated Diabetes","abstract":"<jats:p><jats:italic>Aims</jats:italic>. Hypoglycemia is a limiting factor for achieving stringent glycemic control in diabetes. This study analyzes the frequency and predictors of hypoglycemia in insulin-treated diabetes in an ambulatory setting. <jats:italic>Methods</jats:italic>. A retrospective chart review was performed to study self-monitored blood glucose (SMBG) data for 3 months prior to a patient’s HbA1c test. <jats:italic>Results</jats:italic>. Hypoglycemia occurred more frequently in type 1 than in type 2 diabetes; however, 19% of type 2 diabetes patients did experience at least one episode of severe hypoglycemia. For type 1 diabetes, hypoglycemia had a positive association with glycemic variability and duration of diabetes and a negative association with HbA1c and lowest blood glucose (BG). For type 2 diabetes, a positive association was noted with glycemic variability and a negative association with age and lowest BG. <jats:italic>Conclusions</jats:italic>. Delineating factors predisposing to hypoglycemia in type 2 diabetes is difficult. Lower HbA1c is a potential predictor of hypoglycemia in type 1 but not in type 2 diabetes. Longer duration of diabetes for type 1 and younger age for type 2 are associated with more hypoglycemia. Glycemic variability portends increased risk for hypoglycemia and should be a focus of further research.</jats:p>","journal":"Journal of Diabetes Research","year":2017,"id":602019,"datarank":0.519860385419959,"base_score":3.4657359027997265,"endowment":3.4657359027997265,"self_citation_contribution":0.519860385419959,"citation_network_contribution":0.0,"self_endowment_contribution":0.519860385419959,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":31,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":281796,"name":"Anupam Kotwal","orcid":"0000-0002-4500-8546","position":1,"is_corresponding":false},{"id":599839,"name":"Samir Malkani","orcid":"0000-0001-9076-4327","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Frequency and Predictors of Self-Reported Hypoglycemia in Insulin-Treated Diabetes","abstract":"<jats:p><jats:italic>Aims</jats:italic>. Hypoglycemia is a limiting factor for achieving stringent glycemic control in diabetes. This study analyzes the frequency and predictors of hypoglycemia in insulin-treated diabetes in an ambulatory setting. <jats:italic>Methods</jats:italic>. A retrospective chart review was performed to study self-monitored blood glucose (SMBG) data for 3 months prior to a patient’s HbA1c test. <jats:italic>Results</jats:italic>. Hypoglycemia occurred more frequently in type 1 than in type 2 diabetes; however, 19% of type 2 diabetes patients did experience at least one episode of severe hypoglycemia. For type 1 diabetes, hypoglycemia had a positive association with glycemic variability and duration of diabetes and a negative association with HbA1c and lowest blood glucose (BG). For type 2 diabetes, a positive association was noted with glycemic variability and a negative association with age and lowest BG. <jats:italic>Conclusions</jats:italic>. Delineating factors predisposing to hypoglycemia in type 2 diabetes is difficult. Lower HbA1c is a potential predictor of hypoglycemia in type 1 but not in type 2 diabetes. Longer duration of diabetes for type 1 and younger age for type 2 are associated with more hypoglycemia. Glycemic variability portends increased risk for hypoglycemia and should be a focus of further research.</jats:p>","is_dataset_classified":null,"base_score":3.4657359027997265,"endowment":3.4657359027997265,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"28913365","pmcid":"PMC5585629","openalex_id":"https://openalex.org/W2746097460","authors":[],"funders":[],"total_grants":0,"fwci":1.4055,"citation_percentile":0.8252787,"influential_citations":0,"citation_trend":[{"year":2018,"count":3},{"year":2019,"count":3},{"year":2020,"count":3},{"year":2021,"count":5},{"year":2022,"count":3},{"year":2023,"count":6},{"year":2024,"count":4},{"year":2025,"count":4}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"http://downloads.hindawi.com/journals/jdr/2017/7425925.pdf","host_type":"journal"},{"url":"http://downloads.hindawi.com/journals/jdr/2017/7425925.pdf","host_type":"publisher"},{"url":"http://downloads.hindawi.com/journals/jdr/2017/7425925.xml","host_type":"publisher"},{"url":"https://doi.org/10.1155/2017/7425925","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/28913365","host_type":"repository"},{"url":"https://escholarship.umassmed.edu/oapubs/3231","host_type":"repository"},{"url":"https://doaj.org/article/599aa46f8f514a79bb7d24794b29f8e5","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5585629","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC5585629","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC5585629?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Diabetes Management and Research","Diabetes, Cardiovascular Risks, and Lipoproteins","Diabetes and associated disorders","Adult","Aged","Aged, 80 and over","Blood Glucose","Blood Glucose Self-Monitoring","Diabetes Mellitus, Type 1","Diabetes Mellitus, Type 2","Diagnostic Self Evaluation","Female","Glycated Hemoglobin","Humans","Hypoglycemia","Hypoglycemic Agents","Insulin","Male","Middle Aged","Retrospective Studies","Risk Factors"],"mesh_terms":["Adult","Aged","Aged, 80 and over","Blood Glucose","Diabetes Mellitus, Type 1","Diabetes Mellitus, Type 2","Female","Glycated Hemoglobin","Humans","Hypoglycemia","Hypoglycemic Agents","Insulin","Male","Middle Aged","Retrospective Studies","Risk Factors","Blood Glucose Self-Monitoring","Diagnostic Self Evaluation"],"keywords":["Hypoglycemia","Diabetes mellitus","Insulin","Medicine","Internal medicine","Endocrinology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-29T18:03:22.367957Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}