{"doi":"10.1152/physiol.00022.2017","title":"Comparative Physiology of Nociception and Pain","abstract":"<jats:p>The study of diverse animal groups allows us to discern the evolution of the neurobiology of nociception. Nociception functions as an important alarm system alerting the individual to potential and actual tissue damage. All animals possess nociceptors, and, in some animal groups, it has been demonstrated that there are consistent physiological mechanisms underpinning the nociceptive system. This review considers the comparative biology of nociception and pain from an evolutionary perspective.</jats:p>","journal":"Physiology","year":2018,"id":36180,"datarank":4.838323789206909,"base_score":5.4680601411351315,"endowment":5.4680601411351315,"self_citation_contribution":0.8202090211702698,"citation_network_contribution":4.0181147680366385,"self_endowment_contribution":0.8202090211702698,"citer_contribution":4.0181147680366385,"corpus_percentile":null,"corpus_rank":null,"citation_count":236,"citer_count":200,"citers_with_citation_signal":151,"citers_with_endowment":151,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":183759,"name":"Lynne U. Sneddon","orcid":"0000-0001-9787-3948","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":5.4680601411351315,"endowment":5.4680601411351315,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"29212893","pmcid":null,"openalex_id":"https://openalex.org/W2775213504","authors":[],"funders":[{"funder_name":"National Centre for the Replacement, Refinement and Reduction of Animals in Research","grant_id":"NC/K000888/1","title":null}],"total_grants":1,"fwci":6.6107,"citation_percentile":0.9740105,"influential_citations":9,"citation_trend":[{"year":2017,"count":1},{"year":2018,"count":3},{"year":2019,"count":16},{"year":2020,"count":22},{"year":2021,"count":22},{"year":2022,"count":48},{"year":2023,"count":43},{"year":2024,"count":27},{"year":2025,"count":45},{"year":2026,"count":8}],"oa_status":"closed","license":null,"oa_locations":[{"url":"https://www.physiology.org/doi/pdf/10.1152/physiol.00022.2017","host_type":"BRONZE"},{"url":"https://doi.org/10.1152/physiol.00022.2017","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/29212893","host_type":"repository"}],"fields_of_study":["Pain Mechanisms and Treatments","Olfactory and Sensory Function Studies","Ion Channels and Receptors","Medicine","Biology","Animals","Biological Evolution","Humans","Nociception","Nociceptors","Pain","Species Specificity"],"mesh_terms":["Animals","Biological Evolution","Humans","Nociceptors","Pain","Species Specificity","Nociception"],"keywords":["Nociception","Nociceptor","Neuroscience","Medicine","Psychology","Receptor","Internal medicine"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-10T14:38:23.219943Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}