{"doi":"10.1152/japplphysiol.00376.2020","title":"Variations in loop gain and arousal threshold during NREM sleep are affected by time of day over a 24-hour period in participants with obstructive sleep apnea","abstract":"Loop gain and the arousal threshold during non-rapid eye movement (NREM) sleep are greater in the morning compared with the afternoon and evening. Loop gain measures are correlated to chemoreflex sensitivity and the critical closing pressure measured during NREM sleep in the evening, morning, and afternoon. Breathing (in)stability and efficaciousness of treatments for obstructive sleep apnea may be modulated by a circadian rhythmicity in loop gain and the arousal threshold.","journal":"Journal of Applied Physiology","year":2020,"id":81324,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":14,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9614,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":421414,"name":"Mohamad El‐Chami","orcid":null,"position":1,"is_corresponding":false},{"id":421415,"name":"David Shaheen","orcid":null,"position":2,"is_corresponding":false},{"id":421416,"name":"Blake Ivers","orcid":null,"position":3,"is_corresponding":false},{"id":420589,"name":"Gino S. Panza","orcid":"0000-0002-0228-9843","position":4,"is_corresponding":false},{"id":420590,"name":"M. Safwan Badr","orcid":"0000-0001-5769-5243","position":5,"is_corresponding":false},{"id":420591,"name":"Ho‐Sheng Lin","orcid":"0000-0002-6765-1727","position":6,"is_corresponding":false},{"id":390634,"name":"Jason H. Mateika","orcid":"0000-0001-6453-3568","position":7,"is_corresponding":false},{"id":420588,"name":"Shipra Puri","orcid":"0000-0003-1268-3542","position":0,"is_corresponding":true}],"reference_count":57,"raw_metadata":null,"created_at":"2026-07-18T21:52:34.401799Z","pmid":"32790595","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}