{"doi":"10.1152/japplphysiol.00292.2020","title":"Sex-specific alterations in blood-borne factors in physically inactive individuals are detrimental to endothelial cell functions","abstract":"Serum from sedentary women caused impaired endothelial migration, whereas serum from sedentary men elicited increased endothelial reactive oxygen species production as compared with serum from their endurance-trained counterparts. Select CVD-related circulating microRNAs (ci-miRs) were higher in men than women, while ci-miRs-140-5p and 145-5p were also higher in sedentary versus trained men and/or women. Our data suggest that alterations in circulating factors may contribute to the protective effects of habitual exercise and sex on vascular health.","journal":"Journal of Applied Physiology","year":2020,"id":108127,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":5,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9517,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":409769,"name":"Rian Q. Landers‐Ramos","orcid":"0000-0002-3092-2538","position":1,"is_corresponding":false},{"id":518804,"name":"Daniel D. Shill","orcid":null,"position":2,"is_corresponding":false},{"id":518212,"name":"Catherine B. Springer","orcid":"0000-0001-7598-3679","position":3,"is_corresponding":false},{"id":397978,"name":"James M. Hagberg","orcid":"0000-0002-3897-0059","position":4,"is_corresponding":false},{"id":397974,"name":"Ryan M. Sapp","orcid":"0000-0003-3769-4723","position":0,"is_corresponding":true}],"reference_count":92,"raw_metadata":null,"created_at":"2026-07-18T23:12:39.385256Z","pmid":"32730175","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}