{"doi":"10.1148/ryct.2021210199","title":"Late Gadolinium Enhancement after COVID-19 Vaccination","abstract":"A previously healthy 16-year-old female patient experi- enced chest pain 2 days after the second dose of the Pfizer-BioNTech COVID-19 vaccine.Workup revealed elevated high-sensitivity cardiac troponin T level and electrocardiographic abnormalities, prompting hospitalization with diagnosis of myocarditis.Peak high-sensitivity cardiac troponin T level was 3492 pg/mL (reference range, 0-19 pg/mL); three echocardiograms were normal.Nonsteroidal anti-inflammatory drug therapy resulted in symptomatic improvement.Cardiac MRI performed 6 weeks after hospitalization revealed normal biventricular function and no myocardial edema.Late gadolinium enhancement (LGE) imaging showed subepicardial LGE of the basal inferolateral and inferior walls extending to the midventricular anterolateral, inferolateral, and inferior walls and apical lateral wall (Figure).Recent reports raise concern for acute myocarditis following COVID-19 vaccination (1-3); however, definite proof about the direct link between COVID-19 vaccine and myocarditis is still pending.Although long-term implications are unclear, the extensive LGE in this case seen well past resolution of acute symptoms raises concern for ventricular arrhythmia, future diastolic dysfunction, and other sequelae.Further evaluation of patients after symptomatic recovery should be considered given unknown natural history.","journal":"Radiology Cardiothoracic Imaging","year":2021,"id":202882,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9546,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":333422,"name":"Mark D. Norris","orcid":"0000-0002-3498-5931","position":1,"is_corresponding":false},{"id":734822,"name":"Olivia Frosch","orcid":"0000-0003-2241-7838","position":2,"is_corresponding":false},{"id":783513,"name":"Prachi Agarwal","orcid":"0000-0002-4439-6970","position":3,"is_corresponding":false},{"id":742194,"name":"Hunter C. Wilson","orcid":"0000-0003-2087-7478","position":0,"is_corresponding":true}],"reference_count":3,"raw_metadata":null,"created_at":"2026-07-18T23:51:14.206397Z","pmid":"34778788","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}