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There was no change in the serum IgG specific for Aspergillus fumigatus (mean (SE) change -4% (10%)) or symptoms of chronic cough and haemoptysis. In two of the three patients who continued treatment beyond six months symptoms and radiographic appearances improved and a temporary reduction in A fumigatus specific IgG occurred in one patient. Further experience of the effects of longer treatment are needed before oral itraconazole can be recommended for aspergilloma.","is_dataset_classified":null,"base_score":4.418840607796598,"endowment":4.418840607796598,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"1663275","pmcid":"PMC1021040","openalex_id":"https://openalex.org/W2016668117","authors":[],"funders":[],"total_grants":0,"fwci":1.3633,"citation_percentile":0.80784053,"influential_citations":0,"citation_trend":[{"year":2012,"count":2},{"year":2013,"count":8},{"year":2014,"count":3},{"year":2015,"count":1},{"year":2016,"count":3},{"year":2017,"count":4},{"year":2018,"count":2},{"year":2019,"count":5},{"year":2020,"count":2},{"year":2021,"count":2},{"year":2022,"count":2},{"year":2024,"count":1},{"year":2025,"count":1}],"oa_status":"bronze","license":null,"oa_locations":[{"url":"https://thorax.bmj.com/content/thoraxjnl/46/11/839.full.pdf","host_type":"journal"},{"url":"https://thorax.bmj.com/content/thoraxjnl/46/11/839.full.pdf","host_type":"publisher"},{"url":"https://syndication.highwire.org/content/doi/10.1136/thx.46.11.839","host_type":"publisher"},{"url":"https://doi.org/10.1136/thx.46.11.839","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/1663275","host_type":"repository"},{"url":"https://research.manchester.ac.uk/en/publications/1a9bde29-8754-4ea0-9f6a-eb86109f296c","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1021040","host_type":"repository"},{"url":"https://www.research.manchester.ac.uk/portal/en/publications/treatment-of-pulmonary-aspergilloma-with-itraconazole(1a9bde29-8754-4ea0-9f6a-eb86109f296c).html","host_type":"repository"},{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1021040/pdf/thorax00359-0053.pdf","host_type":"repository"}],"fields_of_study":["Antifungal resistance and susceptibility","Infectious Diseases and Mycology","Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis"],"mesh_terms":["Antibodies, Fungal","Antifungal Agents","Aspergillosis","Aspergillus fumigatus","Female","Humans","Immunoglobulin G","Ketoconazole","Lung","Lung Diseases, Fungal","Male","Middle Aged","Radiography","Itraconazole"],"keywords":["Itraconazole","Aspergilloma","Medicine","Aspergillus fumigatus","Aspergillosis","Allergic bronchopulmonary aspergillosis","Internal medicine","Gastroenterology","Surgery","Dermatology","Immunology","Antifungal","Antibody","Immunoglobulin E"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-08T18:15:50.552137Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}