{"doi":"10.1136/oem-2021-epi.76","title":"O-303 The role of occupational exposures in lung cancer risk among women: preliminary results from a pooled case-control study of lung cancer","abstract":null,"journal":"Oral Presentations","year":2021,"id":598087,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1241336,"name":"Vikki Ho","orcid":"0000-0002-0724-7917","position":1,"is_corresponding":false},{"id":58401,"name":"Jack Siemiatycki","orcid":"0000-0002-9042-8582","position":2,"is_corresponding":false},{"id":1121592,"name":"Mengting Xu","orcid":"0000-0002-6751-1986","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"O-303 The role of occupational exposures in lung cancer risk among women: preliminary results from a pooled case-control study of lung cancer","abstract":"<h3>Introduction</h3> Lung cancer is the most common cause of cancer death among women. However, little is known regarding occupational risk factors for lung cancer in women. <h3>Objective</h3> To investigate possible associations between selected occupational agents and lung cancer risk among women. <h3>Methods</h3> We pooled data from ten case-control studies of lung cancer with detailed lifetime occupational and smoking history. The current analysis was restricted to working women, including 3040 cases and 4186 controls. To assess occupational exposure, we used the Canadian Job-Exposure Matrix (CANJEM). Linking participants’ jobs to the CANJEM allows the estimation of probability, and frequency of exposure to a list of 258 agents. This analysis was restricted to 36 most prevalent occupational agents in our sample of women. The association between lung cancer risk and lifetime ever exposure, duration of exposure, and cumulative exposure for each agent was estimated in separate logistic regression models, adjusted for smoking and other selected covariates. <h3>Results</h3> Most agents we examined were not associated with lung cancer. We observed an increased risk of lung cancer among women occupationally exposed to cooking fumes for over 10 years (OR(95%CI)=1.73(1.09–2.82)). Statistically significant decreased risks of lung cancer were observed among women exposed to various textile fibres, especially among long-duration workers. The results regarding the various textile agents have not been mutually controlled yet. When restricting to never smokers, increased risks of lung cancer were observed among women exposed to metallic dust, isopropanol, and aliphatic alcohols, with OR point estimates for ever exposure ranging from 1.5 to 1.7. <h3>Conclusion</h3> Our preliminary results indicate that occupational exposure to cooking fumes is associated with an increased lung cancer risk in women, while exposures to various textile fibres seem to be associated with a decreased lung cancer risk.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"21097893","pmcid":null,"openalex_id":"https://openalex.org/W3210658462","authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"bronze","license":null,"oa_locations":[{"url":"https://oem.bmj.com/content/oemed/78/Suppl_1/A29.1.full.pdf","host_type":"journal"},{"url":"https://oem.bmj.com/content/oemed/78/Suppl_1/A29.1.full.pdf","host_type":"publisher"},{"url":"https://syndication.highwire.org/content/doi/10.1136/OEM-2021-EPI.76","host_type":"publisher"},{"url":"https://doi.org/10.1136/oem-2021-epi.76","host_type":"journal"}],"fields_of_study":["Occupational and environmental lung diseases"],"mesh_terms":[],"keywords":["Lung cancer","Medicine","Logistic regression","Cancer","Job-exposure matrix","Case-control study","Environmental health","Occupational exposure","Internal medicine"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-28T15:00:07.511900Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}