{"doi":"10.1136/ard.2005.037994","title":"EULAR report on the use of ultrasonography in painful knee osteoarthritis. Part 1: Prevalence of inflammation in osteoarthritis","abstract":null,"journal":"Annals of the Rheumatic Diseases","year":2005,"id":625983,"datarank":0.850998490075724,"base_score":5.673323267171493,"endowment":5.673323267171493,"self_citation_contribution":0.850998490075724,"citation_network_contribution":0.0,"self_endowment_contribution":0.850998490075724,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":290,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1619165,"name":"P Conaghan","orcid":null,"position":1,"is_corresponding":false},{"id":1619166,"name":"M Le Bars","orcid":null,"position":2,"is_corresponding":false},{"id":1619167,"name":"G Baron","orcid":null,"position":3,"is_corresponding":false},{"id":1619168,"name":"W Grassi","orcid":null,"position":4,"is_corresponding":false},{"id":1619169,"name":"E Martin-Mola","orcid":null,"position":5,"is_corresponding":false},{"id":1619170,"name":"R Wakefield","orcid":null,"position":6,"is_corresponding":false},{"id":1619172,"name":"J-L Brasseur","orcid":null,"position":7,"is_corresponding":false},{"id":1619173,"name":"A So","orcid":null,"position":8,"is_corresponding":false},{"id":1619174,"name":"M Backhaus","orcid":null,"position":9,"is_corresponding":false},{"id":1619175,"name":"M Malaise","orcid":null,"position":10,"is_corresponding":false},{"id":1619176,"name":"G Burmester","orcid":null,"position":11,"is_corresponding":false},{"id":1619177,"name":"N Schmidely","orcid":null,"position":12,"is_corresponding":false},{"id":1619178,"name":"P Ravaud","orcid":null,"position":13,"is_corresponding":false},{"id":1619179,"name":"M Dougados","orcid":null,"position":14,"is_corresponding":false},{"id":1619180,"name":"P Emery","orcid":null,"position":15,"is_corresponding":false},{"id":1619164,"name":"M A D'Agostino","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"EULAR report on the use of ultrasonography in painful knee osteoarthritis. Part 1: Prevalence of inflammation in osteoarthritis","abstract":"<h4>Objectives</h4>To assess the prevalence of inflammation in subjects with chronic painful knee osteoarthritis (OA), as determined by the presence of synovitis or joint effusion at ultrasonography (US); and to evaluate the correlation between synovitis, effusion, and clinical parameters.<h4>Methods</h4>A cross sectional, multicentre, European study was conducted under the umbrella of EULAR-ESCISIT.<h4>Subjects</h4>had primary chronic knee OA (ACR criteria) with pain during physical activity >or=30 mm for at least 48 hours. Clinical parameters were collected by a rheumatologist and an US examination of the painful knee was performed by a radiologist or rheumatologist within 72 hours of the clinical examination. Ultrasonographic synovitis was defined as synovial thickness >or=4 mm and diffuse or nodular appearance, and a joint effusion was defined as effusion depth >or=4 mm.<h4>Results</h4>600 patients with painful knee OA were analysed. At US 16 (2.7%) had synovitis alone, 85 (14.2%) had both synovitis and effusion, 177 (29.5%) had joint effusion alone, and 322 (53.7%) had no inflammation according to the definitions employed. Multivariate analysis showed that inflammation seen by US correlated statistically with advanced radiographic disease (Kellgren-Lawrence grade >or=3; odds ratio (OR)=2.20 and 1.91 for synovitis and joint effusion, respectively), and with clinical signs and symptoms suggestive of an inflammatory \"flare\", such as joint effusion on clinical examination (OR=1.97 and 2.70 for synovitis and joint effusion, respectively) or sudden aggravation of knee pain (OR=1.77 for joint effusion).<h4>Conclusion</h4>US can detect synovial inflammation and effusion in painful knee OA, which correlate significantly with knee synovitis, effusion, and clinical parameters suggestive of an inflammatory \"flare\".","is_dataset_classified":null,"base_score":5.673323267171493,"endowment":5.673323267171493,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"15878903","pmcid":"PMC1755310","openalex_id":"https://openalex.org/W2137934350","authors":[],"funders":[],"total_grants":0,"fwci":5.7559,"citation_percentile":0.96604665,"influential_citations":0,"citation_trend":[{"year":2012,"count":11},{"year":2013,"count":13},{"year":2014,"count":15},{"year":2015,"count":22},{"year":2016,"count":13},{"year":2017,"count":10},{"year":2018,"count":16},{"year":2019,"count":12},{"year":2020,"count":15},{"year":2021,"count":17},{"year":2022,"count":11},{"year":2023,"count":14},{"year":2024,"count":18},{"year":2025,"count":10},{"year":2026,"count":3}],"oa_status":"green","license":"other-oa","oa_locations":[{"url":"https://orbi.uliege.be/handle/2268/72431","host_type":"repository"},{"url":"https://orbi.uliege.be/handle/2268/72431","host_type":"repository"},{"url":"https://api.elsevier.com/content/article/PII:S0003496724203599?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0003496724203599?httpAccept=text/plain","host_type":"publisher"},{"url":"https://syndication.highwire.org/content/doi/10.1136/ard.2005.037994","host_type":"publisher"},{"url":"https://doi.org/10.1136/ard.2005.037994","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/15878903","host_type":"repository"},{"url":"https://iris.unil.ch/handle/iris/165082","host_type":"repository"},{"url":"http://ard.bmj.com/cgi/content/short/64/12/1703","host_type":"repository"},{"url":"http://ard.bmj.com/cgi/content/short/ard.2005.037994v1","host_type":"repository"},{"url":"http://ard.bmj.com/cgi/content/short/ard.2005.037994v2","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1755310","host_type":"repository"},{"url":"https://serval.unil.ch/notice/serval:BIB_8D6258BA03FA","host_type":"repository"}],"fields_of_study":["Osteoarthritis Treatment and Mechanisms","Musculoskeletal synovial abnormalities and treatments","Rheumatoid Arthritis Research and Therapies","Aged","Cross-Sectional Studies","Europe","Exudates and Transudates","Female","Humans","Knee Joint","Male","Middle Aged","Multivariate Analysis","Osteoarthritis, Knee","Pain Measurement","Prevalence","Severity of Illness Index","Synovitis","Ultrasonography"],"mesh_terms":["Aged","Cross-Sectional Studies","Europe","Exudates and Transudates","Female","Humans","Knee Joint","Male","Middle Aged","Pain Measurement","Severity of Illness Index","Synovitis","Ultrasonography","Prevalence","Multivariate Analysis","Osteoarthritis, Knee"],"keywords":["Medicine","Synovitis","Effusion","Joint effusion","Osteoarthritis","Physical examination","Internal medicine","Knee Joint","Arthritis","Surgery","Radiology","Pathology","Magnetic resonance imaging"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"doi"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-04T11:49:50.450777Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}