{"doi":"10.1128/spectrum.04240-22","title":"mRNA Vaccine Mitigates SARS-CoV-2 Infections and COVID-19","abstract":"SARS-CoV-2 continues to disrupt everyday life and cause excess morbidity and mortality worldwide. Vaccination has been key to quelling the impact of this respiratory pathogen, and mRNA vaccines have led the charge on this front. However, the emergence of SARS-CoV-2 variants has sparked fears regarding vaccine efficacy. Furthermore, SARS-CoV-2 vaccines continue to be unevenly distributed across the globe. For these reasons and despite the success of emergency authorized and licensed SARS-CoV-2 vaccines, additional vaccines are needed to meet public health demands. The studies presented here are significant as they demonstrate robust protective efficacy of mRNA vaccines developed by GreenLight Biosciences against not only wild-type SARS-CoV-2, but also Alpha and Beta variants. These results support the progression of GreenLight Biosciences SARS-CoV-2 mRNA vaccines to clinical trials as another defense against SARS-CoV-2.","journal":"Microbiology Spectrum","year":2023,"id":360104,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":9,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9464,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":353265,"name":"Sherri L. Surman","orcid":"0000-0003-4199-661X","position":1,"is_corresponding":false},{"id":354717,"name":"Bart G. Jones","orcid":null,"position":2,"is_corresponding":false},{"id":354716,"name":"Robert E. Sealy","orcid":null,"position":3,"is_corresponding":false},{"id":514296,"name":"Trushar Jeevan","orcid":null,"position":4,"is_corresponding":false},{"id":679934,"name":"Christopher J.H. Davitt","orcid":"0000-0002-1081-5284","position":5,"is_corresponding":false},{"id":687037,"name":"Sergei Pustylnikov","orcid":"0000-0002-0977-1640","position":6,"is_corresponding":false},{"id":502614,"name":"Tamarand L. Darling","orcid":"0000-0001-6640-9165","position":7,"is_corresponding":false},{"id":334926,"name":"Adrianus C. M. Boon","orcid":"0000-0002-4700-8224","position":8,"is_corresponding":false},{"id":354718,"name":"Julia L. Hurwitz","orcid":null,"position":9,"is_corresponding":false},{"id":1111529,"name":"Marcelo M. Samsa","orcid":"0009-0001-2639-8518","position":10,"is_corresponding":false},{"id":105444,"name":"Richard J. Webby","orcid":"0000-0002-4397-7132","position":11,"is_corresponding":false},{"id":620554,"name":"Christina Kackos","orcid":"0000-0002-5329-4175","position":0,"is_corresponding":true}],"reference_count":35,"raw_metadata":null,"created_at":"2026-07-19T01:14:01.896928Z","pmid":"36695597","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}