{"doi":"10.1128/spectrum.00324-23","title":"Serodominant SARS-CoV-2 Nucleocapsid Peptides Map to Unstructured Protein Regions","abstract":"As SARS-CoV-2 continues to evolve, a structural and genetic understanding of key viral epitopes will be essential to the development of next-generation diagnostics and vaccines. This study uses structural biology and epitope mapping to define the antigenic regions of the viral nucleocapsid protein in sera from a cohort of COVID-19 patients with diverse clinical outcomes. These results are interpreted in the context of prior structural and epitope mapping studies as well as in the context of emergent viral variants. This report serves as a resource for synthesizing the current state of the field toward improving strategies for future diagnostic and therapeutic design.","journal":"Microbiology Spectrum","year":2023,"id":357180,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":14,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.959,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":36751,"name":"Nicole L. Inniss","orcid":"0000-0002-1510-7412","position":1,"is_corresponding":false},{"id":863610,"name":"Ted Ling-Hu","orcid":"0000-0002-5856-9158","position":2,"is_corresponding":false},{"id":530033,"name":"G. Minasov","orcid":"0000-0001-5460-3462","position":3,"is_corresponding":false},{"id":706992,"name":"G. Wiersum","orcid":null,"position":4,"is_corresponding":false},{"id":493829,"name":"Mónica Rosas‐Lemus","orcid":"0000-0002-6243-0271","position":5,"is_corresponding":false},{"id":530036,"name":"L. Shuvalova","orcid":"0000-0003-1702-6998","position":6,"is_corresponding":false},{"id":283131,"name":"Chad J. Achenbach","orcid":"0000-0003-4847-7249","position":7,"is_corresponding":false},{"id":36741,"name":"Judd F. Hultquist","orcid":"0000-0001-6424-4280","position":8,"is_corresponding":false},{"id":36778,"name":"Karla J. F. Satchell","orcid":"0000-0003-3274-7611","position":9,"is_corresponding":false},{"id":36801,"name":"Kelly E. R. Bachta","orcid":"0000-0001-8838-5117","position":10,"is_corresponding":false},{"id":828866,"name":"Jacob P. Vandervaart","orcid":null,"position":0,"is_corresponding":true}],"reference_count":57,"raw_metadata":null,"created_at":"2026-07-19T01:13:34.795336Z","pmid":"37191546","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}