{"doi":"10.1128/jvi.01653-21","title":"Pathogenesis of Wild-Type-Like Rhesus Cytomegalovirus Strains following Oral Exposure of Immune-Competent Rhesus Macaques","abstract":"Human cytomegalovirus (HCMV) is globally ubiquitous with high seroprevalence rates in all communities. HCMV infections can occur vertically following mother-to-fetus transmission across the placenta and horizontally following shedding of virus in bodily fluids in HCMV-infected hosts and subsequent exposure of susceptible individuals to virus-laden fluids. Intrauterine HCMV has long been recognized as an infectious threat to fetal growth and development. Since vertical HCMV infections occur following horizontal HCMV transmission to the pregnant mother, the nonhuman primate model of HCMV pathogenesis was used to characterize the virological and immunological parameters of infection following primary mucosal exposures to rhesus cytomegalovirus.","journal":"Journal of Virology","year":2021,"id":200600,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9609,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":513808,"name":"W. L. William Chang","orcid":"0000-0002-1258-7369","position":1,"is_corresponding":false},{"id":652823,"name":"Julia Li","orcid":null,"position":2,"is_corresponding":false},{"id":407574,"name":"Nancy Nguyen","orcid":"0000-0002-2598-2587","position":3,"is_corresponding":false},{"id":472906,"name":"Kimberli A. Schmidt","orcid":"0000-0003-4927-6991","position":4,"is_corresponding":false},{"id":38208,"name":"Philip R. Dormitzer","orcid":"0000-0003-0671-6360","position":5,"is_corresponding":false},{"id":778892,"name":"Xinzhen Yang","orcid":null,"position":6,"is_corresponding":false},{"id":401501,"name":"Peter A. Barry","orcid":"0000-0002-7982-674X","position":7,"is_corresponding":false},{"id":472905,"name":"Yujuan Yue","orcid":"0000-0002-6949-6820","position":0,"is_corresponding":true}],"reference_count":111,"raw_metadata":null,"created_at":"2026-07-18T23:50:48.624274Z","pmid":"34788083","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}