{"doi":"10.1128/jcm.42.10.4686-4696.2004","title":"Accuracy of Phenotypic and Genotypic Testing for Identification of\n Streptococcus pneumoniae\n and Description of\n Streptococcus pseudopneumoniae\n sp. nov","abstract":"ABSTRACT\n \n We have identified an unusual group of viridans group streptococci that resemble\n Streptococcus pneumoniae\n . DNA-DNA homology studies suggested that a subset of these isolates represent a novel species that may be included in the\n S. oralis-\n S. mitis\n group of viridans group streptococci. We suggest that this novel species be termed\n Streptococcus pseudopneumoniae\n . A combination of phenotypic and genetic reactions allows its identification.\n S. pseudopneumoniae\n strains do not have pneumococcal capsules, are resistant to optochin (inhibition zones, less than 14 mm) when they are incubated under an atmosphere of increased CO\n 2\n but are susceptible to optochin (inhibition zones, >14 mm) when they are incubated in ambient atmospheres, are not soluble in bile, and are positive by the GenProbe AccuProbe Pneumococcus test. The bile solubility test is more specific than the optochin test for identification of\n S. pneumoniae\n . Genetic tests for pneumolysin (\n ply\n ) and manganese-dependent superoxide dismutase (\n sodA\n ) and identification tests with a commercial probe, AccuProbe Pneumococcus, do not discriminate between the new species and\n S. pneumoniae\n .\n ","journal":"Journal of Clinical Microbiology","year":2004,"id":651402,"datarank":0.8306001400527806,"base_score":5.537334267018537,"endowment":5.537334267018537,"self_citation_contribution":0.8306001400527806,"citation_network_contribution":0.0,"self_endowment_contribution":0.8306001400527806,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":253,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1277505,"name":"Claire Poyart","orcid":"0000-0003-2158-6293","position":1,"is_corresponding":false},{"id":1698841,"name":"Patrick Trieu-Cuot","orcid":null,"position":2,"is_corresponding":false},{"id":1698842,"name":"Gilles Quesne","orcid":null,"position":3,"is_corresponding":false},{"id":1698843,"name":"Maria da GloĢria S. Carvalho","orcid":null,"position":4,"is_corresponding":false},{"id":1698844,"name":"Arnold G. Steigerwalt","orcid":null,"position":5,"is_corresponding":false},{"id":1698845,"name":"Roger E. Morey","orcid":null,"position":6,"is_corresponding":false},{"id":1623942,"name":"Delois Jackson","orcid":null,"position":7,"is_corresponding":false},{"id":1698846,"name":"Ross J. Davidson","orcid":null,"position":8,"is_corresponding":false},{"id":1698847,"name":"Richard R. Facklam","orcid":null,"position":9,"is_corresponding":false},{"id":1698840,"name":"Judy C. Arbique","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Accuracy of Phenotypic and Genotypic Testing for Identification of\n Streptococcus pneumoniae\n and Description of\n Streptococcus pseudopneumoniae\n sp. nov","abstract":"ABSTRACT\n \n We have identified an unusual group of viridans group streptococci that resemble\n Streptococcus pneumoniae\n . DNA-DNA homology studies suggested that a subset of these isolates represent a novel species that may be included in the\n S. oralis-\n S. mitis\n group of viridans group streptococci. We suggest that this novel species be termed\n Streptococcus pseudopneumoniae\n . A combination of phenotypic and genetic reactions allows its identification.\n S. pseudopneumoniae\n strains do not have pneumococcal capsules, are resistant to optochin (inhibition zones, less than 14 mm) when they are incubated under an atmosphere of increased CO\n 2\n but are susceptible to optochin (inhibition zones, >14 mm) when they are incubated in ambient atmospheres, are not soluble in bile, and are positive by the GenProbe AccuProbe Pneumococcus test. The bile solubility test is more specific than the optochin test for identification of\n S. pneumoniae\n . Genetic tests for pneumolysin (\n ply\n ) and manganese-dependent superoxide dismutase (\n sodA\n ) and identification tests with a commercial probe, AccuProbe Pneumococcus, do not discriminate between the new species and\n S. pneumoniae\n .\n ","is_dataset_classified":null,"base_score":5.537334267018537,"endowment":5.537334267018537,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"15472328","pmcid":"PMC522306","openalex_id":"https://openalex.org/W2141992911","authors":[],"funders":[],"total_grants":0,"fwci":6.1101,"citation_percentile":0.96883943,"influential_citations":0,"citation_trend":[{"year":2012,"count":21},{"year":2013,"count":16},{"year":2014,"count":12},{"year":2015,"count":15},{"year":2016,"count":10},{"year":2017,"count":12},{"year":2018,"count":8},{"year":2019,"count":14},{"year":2020,"count":14},{"year":2021,"count":15},{"year":2022,"count":5},{"year":2023,"count":10},{"year":2024,"count":7},{"year":2025,"count":3},{"year":2026,"count":2}],"oa_status":"green","license":"https://journals.asm.org/non-commercial-tdm-license","oa_locations":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/522306","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/522306","host_type":"repository"},{"url":"https://journals.asm.org/doi/pdf/10.1128/JCM.42.10.4686-4696.2004","host_type":"publisher"},{"url":"https://doi.org/10.1128/jcm.42.10.4686-4696.2004","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/15472328","host_type":"repository"},{"url":"http://europepmc.org/pmc/articles/PMC522306","host_type":"repository"}],"fields_of_study":["Pneumonia and Respiratory Infections","Streptococcal Infections and Treatments","Infective Endocarditis Diagnosis and Management"],"mesh_terms":["Bile","Culture Media","DNA, Ribosomal","Genotype","Humans","Molecular Sequence Data","Nucleic Acid Hybridization","Phenotype","Phylogeny","Quinine","RNA, Ribosomal, 16S","Solubility","Species Specificity","Streptococcus pneumoniae","Bacterial Typing Techniques","Sequence Analysis, DNA","Viridans Streptococci"],"keywords":["Streptococcus pneumoniae","Streptococcus oralis","Microbiology","Streptococcus mitis","Biology","Pneumolysin","Streptococcaceae","Streptococcus","Viridans streptococci","Genotype","Polymerase chain reaction","Bacteria","Genetics","Gene","Antibiotics"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Reduced inequalities"},{"sdg_number":0,"sdg_label":"Peace, Justice and strong institutions"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"gen"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-10T08:55:42.987629Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}