{"doi":"10.1128/jcm.00827-07","title":"Comparison of Plaque- and Flow Cytometry-Based Methods for Measuring Dengue Virus Neutralization","abstract":"<jats:title>ABSTRACT</jats:title><jats:p>As dengue vaccines enter clinical trials, there is a need for rapid and quantitative assays to measure neutralization. We have developed flow-based neutralization assays which generated results similar to those generated by the established, plaque reduction neutralization test. The flow assays are an improvement, as they use human cells and allow for high-throughput screening.</jats:p>","journal":"Journal of Clinical Microbiology","year":2007,"id":22154,"datarank":6.437344839896306,"base_score":4.969813299576001,"endowment":4.969813299576001,"self_citation_contribution":0.7454719949364003,"citation_network_contribution":5.691872844959906,"self_endowment_contribution":0.7454719949364003,"citer_contribution":5.691872844959906,"corpus_percentile":null,"corpus_rank":null,"citation_count":143,"citer_count":108,"citers_with_citation_signal":100,"citers_with_endowment":100,"datacite_reuse_total":8,"is_dataset":false,"is_dataset_confidence":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":140260,"name":"William Messer","orcid":null,"position":1,"is_corresponding":false},{"id":140262,"name":"Laura B. Haymore","orcid":null,"position":2,"is_corresponding":false},{"id":103776,"name":"Aravinda M. de Silva","orcid":null,"position":3,"is_corresponding":false},{"id":140258,"name":"Annette A. Kraus","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":4.969813299576001,"endowment":4.969813299576001,"datacite_reuse_total":8,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"17804661","pmcid":"PMC2168473","openalex_id":"https://openalex.org/W1997966491","authors":[],"funders":[],"total_grants":0,"fwci":2.3259,"citation_percentile":0.87603677,"influential_citations":12,"citation_trend":[{"year":2012,"count":9},{"year":2013,"count":13},{"year":2014,"count":17},{"year":2015,"count":4},{"year":2016,"count":10},{"year":2017,"count":12},{"year":2018,"count":11},{"year":2019,"count":14},{"year":2020,"count":15},{"year":2021,"count":8},{"year":2022,"count":7},{"year":2023,"count":4},{"year":2024,"count":4},{"year":2025,"count":1}],"oa_status":"green","license":"https://journals.asm.org/non-commercial-tdm-license","oa_locations":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2168473","host_type":"repository"},{"url":"https://europepmc.org/articles/pmc2168473?pdf=render","host_type":"GREEN"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2168473","host_type":"repository"},{"url":"https://journals.asm.org/doi/pdf/10.1128/JCM.00827-07","host_type":"publisher"},{"url":"https://doi.org/10.1128/jcm.00827-07","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/17804661","host_type":"repository"}],"fields_of_study":["Mosquito-borne diseases and control","Malaria Research and Control","Viral Infections and Vectors","Medicine","Biology","Dengue Vaccines","Dengue Virus","Flow Cytometry","Humans","Immune Sera","Neutralization Tests","Viral Plaque Assay"],"mesh_terms":["Dengue Virus","Flow Cytometry","Humans","Immune Sera","Neutralization Tests","Viral Plaque Assay","Dengue Vaccines"],"keywords":["Neutralization","Plaque reduction neutralization test","Dengue fever","Flow cytometry","Virology","Dengue virus","Virus quantification","Virus","Biology","Immunology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[{"doi":"10.6084/m9.figshare.13071203.v1","title":"Additional file 1 of The TIRS trial: protocol for a cluster randomized controlled trial assessing the efficacy of preventive targeted indoor residual spraying to reduce Aedes-borne viral illnesses in Merida, Mexico","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.13071203","title":"Additional file 1 of The TIRS trial: protocol for a cluster randomized controlled trial assessing the efficacy of preventive targeted indoor residual spraying to reduce Aedes-borne viral illnesses in Merida, Mexico","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.13071206.v1","title":"Additional file 2 of The TIRS trial: protocol for a cluster randomized controlled trial assessing the efficacy of preventive targeted indoor residual spraying to reduce Aedes-borne viral illnesses in Merida, Mexico","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.13071206","title":"Additional file 2 of The TIRS trial: protocol for a cluster randomized controlled trial assessing the efficacy of preventive targeted indoor residual spraying to reduce Aedes-borne viral illnesses in Merida, Mexico","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.13071209.v1","title":"Additional file 3 of The TIRS trial: protocol for a cluster randomized controlled trial assessing the efficacy of preventive targeted indoor residual spraying to reduce Aedes-borne viral illnesses in Merida, Mexico","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.13071209","title":"Additional file 3 of The TIRS trial: protocol for a cluster randomized controlled trial assessing the efficacy of preventive targeted indoor residual spraying to reduce Aedes-borne viral illnesses in Merida, Mexico","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.20081019.v1","title":"Additional file 1 of A gossypol derivative effectively protects against Zika and dengue virus infection without toxicity","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.20081019","title":"Additional file 1 of A gossypol derivative effectively protects against Zika and dengue virus infection without toxicity","publisher":"figshare","resource_type":"JournalArticle"}],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-06T18:05:50.549370Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}