{"doi":"10.1128/jb.184.5.1444-1448.2002","title":"Charged Amino Acids Conserved in the Aromatic Acid/H\n            <sup>+</sup>\n            Symporter Family of Permeases Are Required for 4-Hydroxybenzoate Transport by PcaK from\n            <i>Pseudomonas putida</i>","abstract":"<jats:title>ABSTRACT</jats:title>\n          <jats:p>\n            Charged amino acids in the predicted transmembrane portion of PcaK, a permease from\n            <jats:italic>Pseudomonas putida</jats:italic>\n            that transports 4-hydroxybenzoate (4-HBA), were required for 4-HBA transport, and they were also required for\n            <jats:italic>P</jats:italic>\n            .\n            <jats:italic>putida</jats:italic>\n            to have a chemotactic response to 4-HBA. An essential amino acid motif (DGXD) containing aspartate residues is located in the first transmembrane segment of PcaK and is conserved in the aromatic acid/H\n            <jats:sup>+</jats:sup>\n            symporter family of the major facilitator superfamily of transporters.\n          </jats:p>","journal":"Journal of Bacteriology","year":2002,"id":668703,"datarank":0.5416376868966337,"base_score":3.6109179126442243,"endowment":3.6109179126442243,"self_citation_contribution":0.5416376868966337,"citation_network_contribution":0.0,"self_endowment_contribution":0.5416376868966337,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":36,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":769032,"name":"Caroline S. Harwood","orcid":"0000-0003-4450-5177","position":1,"is_corresponding":false},{"id":1746272,"name":"Jayna L. Ditty","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Charged Amino Acids Conserved in the Aromatic Acid/H\n            <sup>+</sup>\n            Symporter Family of Permeases Are Required for 4-Hydroxybenzoate Transport by PcaK from\n            <i>Pseudomonas putida</i>","abstract":"<jats:title>ABSTRACT</jats:title>\n          <jats:p>\n            Charged amino acids in the predicted transmembrane portion of PcaK, a permease from\n            <jats:italic>Pseudomonas putida</jats:italic>\n            that transports 4-hydroxybenzoate (4-HBA), were required for 4-HBA transport, and they were also required for\n            <jats:italic>P</jats:italic>\n            .\n            <jats:italic>putida</jats:italic>\n            to have a chemotactic response to 4-HBA. An essential amino acid motif (DGXD) containing aspartate residues is located in the first transmembrane segment of PcaK and is conserved in the aromatic acid/H\n            <jats:sup>+</jats:sup>\n            symporter family of the major facilitator superfamily of transporters.\n          </jats:p>","is_dataset_classified":null,"base_score":3.6109179126442243,"endowment":3.6109179126442243,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"11844776","pmcid":"PMC134867","openalex_id":"https://openalex.org/W2033976445","authors":[],"funders":[{"funder_name":"NIGMS NIH HHS","grant_id":"GM 56665","title":null},{"funder_name":"NIGMS NIH HHS","grant_id":"R01 GM056665","title":null}],"total_grants":2,"fwci":1.1299,"citation_percentile":0.74511245,"influential_citations":0,"citation_trend":[{"year":2012,"count":3},{"year":2013,"count":3},{"year":2014,"count":2},{"year":2015,"count":2},{"year":2016,"count":1},{"year":2017,"count":2},{"year":2018,"count":3},{"year":2022,"count":2},{"year":2025,"count":4}],"oa_status":"green","license":"https://journals.asm.org/non-commercial-tdm-license","oa_locations":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/134867","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/134867","host_type":"repository"},{"url":"https://journals.asm.org/doi/pdf/10.1128/JB.184.5.1444-1448.2002","host_type":"publisher"},{"url":"https://doi.org/10.1128/jb.184.5.1444-1448.2002","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/11844776","host_type":"repository"},{"url":"https://ir.stthomas.edu/biol_pub/15","host_type":"repository"}],"fields_of_study":["Microbial bioremediation and biosurfactants","Enzyme Structure and Function","Chromium effects and bioremediation"],"mesh_terms":["Amino Acid Sequence","Bacterial Proteins","Biological Transport","Carrier Proteins","Cell Membrane","Chemotaxis","Molecular Sequence Data","Mutation","Parabens","Pseudomonas putida","Amino Acids, Aromatic","Membrane Transport Proteins","Symporters"],"keywords":["Major facilitator superfamily","Symporter","Permease","Pseudomonas putida","Biology","Biochemistry","Amino acid","Hydroxybenzoate","Transporter","Transmembrane domain","Transmembrane protein","Aromatic amino acids","Gene","Receptor"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"gen"},{"name":"uniprot"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-14T12:30:52.704166Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}