{"doi":"10.1128/jb.00264-20","title":"Staphylococcus aureus Preferentially Liberates Inorganic Phosphate from Organophosphates in Environments where This Nutrient Is Limiting","abstract":"For bacteria, the preferred form of the essential nutrient phosphate is inorganic monophosphate (P i ), but phosphate can also be extracted from a variety of phosphocompounds. Pathogens, including Staphylococcus aureus , experience P i limitation within the host, suggesting that the use of alternative phosphate sources is important during infection. However, the alternative phosphate sources that can be used by S. aureus and others remain largely unexplored. We screened a library of phosphorus-containing compounds for the ability to support growth as a phosphate source. S. aureus could use a variety of phosphocompounds, including nucleotides, phosphosugars, and phosphoamino acids. Subsequent genetic analysis determined that a majority of these alternative phosphate sources are first processed extracellularly to liberate P i , which is then imported through P i transporters.","journal":"Journal of Bacteriology","year":2020,"id":85255,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":7,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9551,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":436192,"name":"Aleeza J. Leder Macek","orcid":"0000-0002-3952-822X","position":1,"is_corresponding":false},{"id":436193,"name":"Kevin Grudzinski","orcid":"0000-0002-2317-5968","position":2,"is_corresponding":false},{"id":351248,"name":"Jana N. Radin","orcid":"0000-0003-1783-7336","position":3,"is_corresponding":false},{"id":331762,"name":"Thomas E. Kehl‐Fie","orcid":"0000-0001-8234-1113","position":4,"is_corresponding":false},{"id":436191,"name":"Jessica L. Kelliher","orcid":"0000-0001-7734-8337","position":0,"is_corresponding":true}],"reference_count":50,"raw_metadata":null,"created_at":"2026-07-18T21:56:02.794896Z","pmid":"32868400","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}