{"doi":"10.1128/jb.00165-25","title":"<i>Staphylococcus epidermidis</i> —key to understanding biofilms, commensalism, and more","abstract":"ABSTRACT Staphylococcus epidermidis , a ubiquitous inhabitant of human skin, has been known for decades for its capacity to form biofilm-associated infections on indwelling medical devices and has developed into a leading bacterium used in biofilm research. Early investigation on the biofilm matrix focused on S. epidermidis “slime,” and currently, S. epidermidis represents one of the most prevalent organisms for in-vivo biofilm infection models. More recently, S. epidermidis has also become a standard for the investigation of host-commensal interactions on human skin, especially the immune response to colonization that is often called “commensal immunity.” Finally, there are recent efforts to use S. epidermidis as a topically applied vehicle for probiotic pathogen exclusion efforts as well as anti-cancer and vaccination strategies.","journal":"Journal of Bacteriology","year":2025,"id":513070,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":11,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9561,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":268488,"name":"Michaël Otto","orcid":"0000-0002-2222-4115","position":1,"is_corresponding":false},{"id":326526,"name":"Gordon Y. C. Cheung","orcid":"0000-0003-1796-6058","position":0,"is_corresponding":true}],"reference_count":106,"raw_metadata":null,"created_at":"2026-07-19T02:48:11.233009Z","pmid":"40853140","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}