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Pathogenic strains of\n                    <jats:named-content content-type=\"genus-species\">C. difficile</jats:named-content>\n                    produce toxin A (TcdA) and toxin B (TcdB), which can directly kill cells and induce an inflammatory response in the colonic mucosa.\n                  </jats:p>","journal":"Infection and Immunity","year":2021,"id":679147,"datarank":0.4566783656585135,"base_score":3.044522437723423,"endowment":3.044522437723423,"self_citation_contribution":0.4566783656585135,"citation_network_contribution":0.0,"self_endowment_contribution":0.4566783656585135,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":20,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":584079,"name":"Sarah C. 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Pathogenic strains of\n                    <jats:named-content content-type=\"genus-species\">C. difficile</jats:named-content>\n                    produce toxin A (TcdA) and toxin B (TcdB), which can directly kill cells and induce an inflammatory response in the colonic mucosa.\n                  </jats:p>","is_dataset_classified":null,"base_score":3.044522437723423,"endowment":3.044522437723423,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"33468584","pmcid":"PMC8090962","openalex_id":"https://openalex.org/W3124819012","authors":[],"funders":[{"funder_name":"HHS | NIH | National Cancer Institute","grant_id":"CA197570","title":null},{"funder_name":"HHS | NIH | National Cancer Institute","grant_id":"CA236733","title":null},{"funder_name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","grant_id":"AI095755","title":null},{"funder_name":"U.S. Department of Veterans Affairs","grant_id":"BX002943","title":null},{"funder_name":"HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases","grant_id":"DK007673","title":null},{"funder_name":"HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases","grant_id":"DK058404","title":null},{"funder_name":"BLRD VA","grant_id":"I01 BX002943","title":null},{"funder_name":"NCI NIH HHS","grant_id":"P50 CA236733","title":null},{"funder_name":"NCI NIH HHS","grant_id":"R35 CA197570","title":null},{"funder_name":"NIDDK NIH HHS","grant_id":"P30 DK058404","title":null},{"funder_name":"NIAID NIH HHS","grant_id":"T32 AI007281","title":null},{"funder_name":"NIDDK NIH HHS","grant_id":"T32 DK007673","title":null},{"funder_name":"NIAID NIH HHS","grant_id":"R01 AI095755","title":null},{"funder_name":"NIAID NIH HHS","grant_id":"R37 AI095755","title":null}],"total_grants":14,"fwci":0.9292,"citation_percentile":0.77387999,"influential_citations":0,"citation_trend":[{"year":2021,"count":4},{"year":2022,"count":5},{"year":2023,"count":5},{"year":2024,"count":1},{"year":2025,"count":2},{"year":2026,"count":3}],"oa_status":"green","license":"https://journals.asm.org/non-commercial-tdm-license","oa_locations":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8090962","host_type":"repository"},{"url":"https://europepmc.org/articles/pmc8090962?pdf=render","host_type":"GREEN"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8090962","host_type":"repository"},{"url":"https://journals.asm.org/doi/pdf/10.1128/IAI.00543-20","host_type":"publisher"},{"url":"https://doi.org/10.1128/iai.00543-20","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/33468584","host_type":"repository"},{"url":"http://europepmc.org/pmc/articles/PMC8090962","host_type":"repository"}],"fields_of_study":["Clostridium difficile and Clostridium perfringens research","Microscopic Colitis","Gastrointestinal motility and disorders","Medicine","Biology","Animals","Bacterial Proteins","Bacterial Toxins","Clostridioides difficile","Colon","Disease Models, Animal","Disease Susceptibility","Enterocolitis, Pseudomembranous","Enterotoxins","Humans","Immunohistochemistry","Intestinal Mucosa","Mice","Mutant Proteins","Recombinant Proteins"],"mesh_terms":["Animals","Bacterial Proteins","Bacterial Toxins","Colon","Disease Models, Animal","Disease Susceptibility","Enterocolitis, Pseudomembranous","Enterotoxins","Humans","Immunohistochemistry","Intestinal Mucosa","Recombinant Proteins","Clostridioides difficile","Mutant Proteins","Mice"],"keywords":["Clostridioides","Microbiology","Clostridium difficile toxin B","Toxin","Biology","Pathogenesis","Clostridium difficile toxin A","Diarrheal diseases","Recombinant DNA","Enterotoxin","Microbial toxins","Diarrhea","Antibiotics","Clostridium difficile","Virology","Immunology","Medicine","Pathology","Escherichia coli","Gene","Mouse Model","Bacterial Toxin","Acute Colitis","Clostridioides Difficile"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"gen"},{"name":"doi"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-17T12:20:41.940978Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}