{"doi":"10.1128/iai.00326-19","title":"<i>Anopheles gambiae</i>\n            Lacking\n            <i>AgTRIO</i>\n            Inefficiently Transmits\n            <i>Plasmodium berghei</i>\n            to Mice","abstract":"<jats:p>\n            Antibodies to AgTRIO, a mosquito salivary protein, partially reduce the initial\n            <jats:italic>Plasmodium</jats:italic>\n            burden in mice. We therefore silenced\n            <jats:italic>AgTRIO</jats:italic>\n            in mosquitoes and determined the relative contribution of AgTRIO to the ability of\n            <jats:named-content content-type=\"genus-species\">Anopheles gambiae</jats:named-content>\n            to transmit\n            <jats:named-content content-type=\"genus-species\">Plasmodium berghei</jats:named-content>\n            to mice. RNA interference-mediated silencing of\n            <jats:italic>AgTRIO in</jats:italic>\n            <jats:named-content content-type=\"genus-species\">A. gambiae</jats:named-content>\n            resulted in a 60% reduction in\n            <jats:italic>AgTRIO</jats:italic>\n            expression. The decrease in\n            <jats:italic>AgTRIO</jats:italic>\n            expression did not alter the burden of\n            <jats:italic>Plasmodium</jats:italic>\n            sporozoites in mosquito salivary glands.\n          </jats:p>","journal":"Infection and Immunity","year":2019,"id":13731,"datarank":0.8422893659582454,"base_score":3.044522437723423,"endowment":3.044522437723423,"self_citation_contribution":0.4566783656585135,"citation_network_contribution":0.38561100029973194,"self_endowment_contribution":0.4566783656585135,"citer_contribution":0.38561100029973194,"corpus_percentile":null,"corpus_rank":null,"citation_count":20,"citer_count":12,"citers_with_citation_signal":9,"citers_with_endowment":9,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":111421,"name":"Marianna Freudzon","orcid":null,"position":1,"is_corresponding":false},{"id":105564,"name":"Jing Yang","orcid":"0009-0004-6493-5638","position":2,"is_corresponding":false},{"id":111422,"name":"Yuemei Dong","orcid":null,"position":3,"is_corresponding":false},{"id":111423,"name":"George Dimopoulos","orcid":"0000-0001-6755-8111","position":4,"is_corresponding":false},{"id":111424,"name":"Erol Fikrig","orcid":null,"position":5,"is_corresponding":false},{"id":111420,"name":"Yu-Min Chuang","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":3.044522437723423,"endowment":3.044522437723423,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"31285253","pmcid":"PMC6704594","openalex_id":"https://openalex.org/W2956265626","authors":[],"funders":[{"funder_name":"HHS | National Institutes of Health","grant_id":"AR007016-44","title":null},{"funder_name":"NIAMS NIH HHS","grant_id":"T32 AR007016","title":null},{"funder_name":"NCATS NIH HHS","grant_id":"UL1 TR001863","title":null},{"funder_name":"Howard Hughes Medical Institute","grant_id":"","title":null},{"funder_name":"Howard Hughes Medical Institute","grant_id":"","title":null}],"total_grants":5,"fwci":1.3505,"citation_percentile":0.8181953,"influential_citations":0,"citation_trend":[{"year":2020,"count":1},{"year":2021,"count":3},{"year":2022,"count":2},{"year":2023,"count":5},{"year":2024,"count":4},{"year":2025,"count":5}],"oa_status":"bronze","license":"https://journals.asm.org/non-commercial-tdm-license","oa_locations":[{"url":"https://iai.asm.org/content/iai/87/9/e00326-19.full.pdf","host_type":"journal"},{"url":"https://iai.asm.org/content/iai/87/9/e00326-19.full.pdf","host_type":"BRONZE"},{"url":"https://iai.asm.org/content/iai/87/9/e00326-19.full.pdf","host_type":"publisher"},{"url":"https://journals.asm.org/doi/pdf/10.1128/IAI.00326-19","host_type":"publisher"},{"url":"https://doi.org/10.1128/iai.00326-19","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/31285253","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6704594","host_type":"repository"}],"fields_of_study":["Malaria Research and Control","Mosquito-borne diseases and control","Invertebrate Immune Response Mechanisms","Biology","Medicine","Environmental Science","Animals","Anopheles","Cytokines","Disease Models, Animal","Immunization, Passive","Insect Proteins","Malaria","Mice","Mice, Inbred C57BL","Plasmodium berghei"],"mesh_terms":["Animals","Anopheles","Disease Models, Animal","Immunization, Passive","Malaria","Mice, Inbred C57BL","Plasmodium berghei","Cytokines","Insect Proteins","Mice"],"keywords":["Anopheles gambiae","Plasmodium berghei","Biology","Plasmodium (life cycle)","RNA interference","Gene silencing","Virology","Anopheles","Malaria","RNA silencing","RNA","Immunology","Parasite hosting","Genetics","Gene","Plasmodium","Saliva","Inflammation","sporozoite"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-05-31T13:56:45.784000Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}